ID   MLE_HALRO               Reviewed;         151 AA.
AC   P07462;
DT   01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1988, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Myosin catalytic light chain, smooth muscle;
OS   Halocynthia roretzi (Sea squirt) (Cynthia roretzi).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Stolidobranchia;
OC   Pyuridae; Halocynthia.
OX   NCBI_TaxID=7729;
RN   [1]
RP   PROTEIN SEQUENCE, AND ACETYLATION AT ALA-1.
RA   Takagi T., Kudoh S., Konishi K.;
RT   "The amino acid sequence of ascidian (Halocynthia roretzi) myosin light
RT   chains.";
RL   Biochim. Biophys. Acta 874:318-325(1986).
CC   -!- FUNCTION: In molluscan muscle, calcium regulation is associated with
CC       myosin rather than with actin. Muscle myosin contains two types of
CC       light chains: the catalytic light chain, essential for ATPase activity,
CC       and the regulatory light chain, a calcium-binding protein responsible
CC       for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity.
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DR   PIR; B26092; B26092.
DR   AlphaFoldDB; P07462; -.
DR   SMR; P07462; -.
DR   GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   Pfam; PF13833; EF-hand_8; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS50222; EF_HAND_2; 3.
PE   1: Evidence at protein level;
KW   Acetylation; Direct protein sequencing; Motor protein; Muscle protein;
KW   Myosin; Repeat.
FT   CHAIN           1..151
FT                   /note="Myosin catalytic light chain, smooth muscle"
FT                   /id="PRO_0000198723"
FT   DOMAIN          6..41
FT                   /note="EF-hand 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          83..118
FT                   /note="EF-hand 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          119..151
FT                   /note="EF-hand 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   MOD_RES         1
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000269|Ref.1"
SQ   SEQUENCE   151 AA;  16961 MW;  39DC95E3A078ADA6 CRC64;
     ADFSDDRITE CQEAFELFDR SAEGKVFLGQ VGDILRALGQ NPTNGDVTKV LGNPPKEELA
     TKQVSFSEFL PMLAQIERQT EHGSYEDFVE GLRVFDKENN GKIMGAELRH VLSTLGEKMS
     EEEVEESLLQ GQQDPNGCIH YEEFSKYLLE G