ID   MLR_BOMMO               Reviewed;         201 AA.
AC   Q1HPS0; P82214; P82215;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-JUN-2006, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Myosin regulatory light chain 2;
DE            Short=MLC-2;
OS   Bombyx mori (Silk moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Bombycidae; Bombycinae; Bombyx.
OX   NCBI_TaxID=7091;
RN   [1] {ECO:0000312|EMBL:ABF51421.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Niu B.L., Meng Z.Q., Weng H.B., Shen W.F., He L.H., Zheng K.F., Ye S.T.,
RA   Lin T.B., Chen J.E.;
RT   "Blast silkworm EST database for functional genes.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 45-74 AND 77-96.
RC   STRAIN=Xinhang X Keming {ECO:0000269|PubMed:11280994};
RC   TISSUE=Body wall {ECO:0000269|PubMed:11280994}, and
RC   Fat body {ECO:0000269|PubMed:11280994};
RX   PubMed=11280994;
RA   Zhong B.-X.;
RT   "Protein database for several tissues derived from five instar of
RT   silkworm.";
RL   Yi Chuan Xue Bao 28:217-224(2001).
CC   -!- SUBUNIT: Myosin is a hexamer of 2 heavy chains and 4 light chains.
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: This chain binds calcium.
CC       {ECO:0000250|UniProtKB:P02610}.
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DR   EMBL; DQ443332; ABF51421.1; -; mRNA.
DR   RefSeq; NP_001091813.1; NM_001098343.1.
DR   AlphaFoldDB; Q1HPS0; -.
DR   SMR; Q1HPS0; -.
DR   STRING; 7091.BGIBMGA002259-TA; -.
DR   PRIDE; Q1HPS0; -.
DR   GeneID; 778518; -.
DR   KEGG; bmor:778518; -.
DR   CTD; 181775; -.
DR   eggNOG; KOG0031; Eukaryota.
DR   HOGENOM; CLU_061288_9_1_1; -.
DR   OrthoDB; 1435392at2759; -.
DR   Proteomes; UP000005204; Unassembled WGS sequence.
DR   GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   Pfam; PF13833; EF-hand_8; 1.
DR   SMART; SM00054; EFh; 2.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 3.
PE   1: Evidence at protein level;
KW   Calcium; Direct protein sequencing; Metal-binding; Motor protein;
KW   Muscle protein; Myosin; Phosphoprotein; Reference proteome; Repeat.
FT   CHAIN           1..201
FT                   /note="Myosin regulatory light chain 2"
FT                   /id="PRO_0000274812"
FT   DOMAIN          55..90
FT                   /note="EF-hand 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          125..158
FT                   /note="EF-hand 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          159..194
FT                   /note="EF-hand 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   REGION          1..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         68
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         70
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         72
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         79
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   MOD_RES         46
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P24844"
FT   CONFLICT        69
FT                   /note="H -> A (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   201 AA;  22042 MW;  10F858D8CA8EC803 CRC64;
     MADKDKKVKK KKAKEDAPAE EAPAAAAPAG DRQSSRGSRK AKRTGSNVFS MFSQKQVAEF
     KEAFQLMDHD KDGIIGKNDL RATFDSLGRL ASEKELDEMV GEASGPINFT QLLTLFANRM
     SGGSDEDDVV INAFKTFDEE GKIDSERLRH ALMTWGDKFS ADEVDEAYDQ MDIDDKGYID
     TTKLIAMLTA SAEEEEGGEA A