6PGL_BUCBP
ID 6PGL_BUCBP Reviewed; 331 AA.
AC Q89AK3;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=6-phosphogluconolactonase {ECO:0000255|HAMAP-Rule:MF_01605};
DE Short=6-P-gluconolactonase {ECO:0000255|HAMAP-Rule:MF_01605};
DE EC=3.1.1.31 {ECO:0000255|HAMAP-Rule:MF_01605};
GN Name=pgl {ECO:0000255|HAMAP-Rule:MF_01605}; OrderedLocusNames=bbp_274;
OS Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Buchnera.
OX NCBI_TaxID=224915;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bp;
RX PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT "Reductive genome evolution in Buchnera aphidicola.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC -!- FUNCTION: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-
CC phosphogluconate. {ECO:0000255|HAMAP-Rule:MF_01605}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate
CC + H(+); Xref=Rhea:RHEA:12556, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57955, ChEBI:CHEBI:58759; EC=3.1.1.31;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01605};
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step
CC 2/3. {ECO:0000255|HAMAP-Rule:MF_01605}.
CC -!- SIMILARITY: Belongs to the cycloisomerase 2 family. {ECO:0000255|HAMAP-
CC Rule:MF_01605}.
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DR EMBL; AE016826; AAO26999.1; -; Genomic_DNA.
DR RefSeq; WP_011091400.1; NC_004545.1.
DR AlphaFoldDB; Q89AK3; -.
DR SMR; Q89AK3; -.
DR STRING; 224915.bbp_274; -.
DR EnsemblBacteria; AAO26999; AAO26999; bbp_274.
DR GeneID; 56470815; -.
DR KEGG; bab:bbp_274; -.
DR eggNOG; COG2706; Bacteria.
DR HOGENOM; CLU_038716_2_0_6; -.
DR OMA; EGNWPRD; -.
DR OrthoDB; 302683at2; -.
DR UniPathway; UPA00115; UER00409.
DR Proteomes; UP000000601; Chromosome.
DR GO; GO:0017057; F:6-phosphogluconolactonase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.130.10.10; -; 1.
DR HAMAP; MF_01605; 6P_gluconolactonase; 1.
DR InterPro; IPR022528; 6-phosphogluconolactonase_YbhE.
DR InterPro; IPR019405; Lactonase_7-beta_prop.
DR InterPro; IPR011045; N2O_reductase_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR Pfam; PF10282; Lactonase; 1.
DR SUPFAM; SSF50974; SSF50974; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism; Glucose metabolism; Hydrolase; Reference proteome.
FT CHAIN 1..331
FT /note="6-phosphogluconolactonase"
FT /id="PRO_0000171130"
SQ SEQUENCE 331 AA; 37872 MW; C65076CFA856C926 CRC64;
MKQIIYITLA KNQEIEVWKL HDDFSLNLLQ RISTQGEPQP IIISKDKKYL YIGVRPKFKV
YSYKIKADGT LTKHACSTLP GSPNHFEIDH TGKYLFSSSY HFNCLSITPL DTLGIPRPVT
QTIKNIFGCH ASKMNCYNTC LFISALKKDC IYAYNFKKNG KLLKNTRKNF MTNVNFGPRH
LDLQKCNNRL YSVNELNGSV DIWSINSFSN ELILLKNINI MSKNYCNAAW SSDLHISPCE
KFLYVSDRIE NTISIIKLEK DVQNIEKIGH IKTELQPRTF SINSTGENLI VVGEKSNSFS
VYKISKITGL LELKNTYSTG NRPVWISSLM L
