ID   6PGL_CAUVC              Reviewed;         232 AA.
AC   Q9A6N1;
DT   24-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=6-phosphogluconolactonase;
DE            Short=6PGL;
DE            EC=3.1.1.31;
GN   Name=pgl; OrderedLocusNames=CC_2056;
OS   Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=190650;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19089 / CB15;
RX   PubMed=11259647; DOI=10.1073/pnas.061029298;
RA   Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA   Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA   Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA   DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA   Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA   Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA   Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT   "Complete genome sequence of Caulobacter crescentus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC   -!- FUNCTION: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate
CC         + H(+); Xref=Rhea:RHEA:12556, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57955, ChEBI:CHEBI:58759; EC=3.1.1.31;
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC       ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step
CC       2/3.
CC   -!- SIMILARITY: Belongs to the glucosamine/galactosamine-6-phosphate
CC       isomerase family. 6-phosphogluconolactonase subfamily. {ECO:0000305}.
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DR   EMBL; AE005673; AAK24029.1; -; Genomic_DNA.
DR   PIR; A87504; A87504.
DR   RefSeq; NP_420861.1; NC_002696.2.
DR   RefSeq; WP_010919919.1; NC_002696.2.
DR   AlphaFoldDB; Q9A6N1; -.
DR   SMR; Q9A6N1; -.
DR   STRING; 190650.CC_2056; -.
DR   EnsemblBacteria; AAK24029; AAK24029; CC_2056.
DR   KEGG; ccr:CC_2056; -.
DR   PATRIC; fig|190650.5.peg.2075; -.
DR   eggNOG; COG0363; Bacteria.
DR   HOGENOM; CLU_053947_2_1_5; -.
DR   OMA; YQLFEFE; -.
DR   BioCyc; CAULO:CC2056-MON; -.
DR   UniPathway; UPA00115; UER00409.
DR   Proteomes; UP000001816; Chromosome.
DR   GO; GO:0017057; F:6-phosphogluconolactonase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR   CDD; cd01400; 6PGL; 1.
DR   InterPro; IPR005900; 6-phosphogluconolactonase_DevB.
DR   InterPro; IPR006148; Glc/Gal-6P_isomerase.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   InterPro; IPR039104; PGLS.
DR   PANTHER; PTHR11054; PTHR11054; 1.
DR   Pfam; PF01182; Glucosamine_iso; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   TIGRFAMs; TIGR01198; pgl; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..232
FT                   /note="6-phosphogluconolactonase"
FT                   /id="PRO_0000090090"
SQ   SEQUENCE   232 AA;  24234 MW;  8FBEA52F720F87B6 CRC64;
     MPFTPIKLEA FGSREDLYDA AASVLVGALT TAVARHGRVG FAATGGTTPA PVYDRMATMT
     APWDKVTVTL TDERFVPATD ASSNEGLVRR HLLVGEAAKA SFAPLFFDGV SHDESARKAE
     AGVNAATPFG VVLLGVGPDG HFASLFPGNP MLDQGLDLAT DRSVLAVPPS DPAPDLPRLS
     LTLAALTRTD LIVLLVTGAA KKALLDGDVD PALPVAAILK QDRAKVRILW AE