ID   MM22_MAGGM              Reviewed;         195 AA.
AC   V6F2Z8; Q6N0B5;
DT   18-SEP-2019, integrated into UniProtKB/Swiss-Prot.
DT   19-FEB-2014, sequence version 1.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=Magnetosome membrane protein 22 {ECO:0000303|PubMed:14766587};
GN   Name=mm22 {ECO:0000303|PubMed:14766587}; OrderedLocusNames=MGMSRv2__1633;
GN   ORFNames=MGR_3691;
OS   Magnetospirillum gryphiswaldense (strain DSM 6361 / JCM 21280 / NBRC 15271
OS   / MSR-1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Magnetospirillum.
OX   NCBI_TaxID=431944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 3-16, AND
RP   SUBCELLULAR LOCATION.
RC   STRAIN=DSM 6361 / JCM 21280 / NBRC 15271 / MSR-1;
RX   PubMed=14766587; DOI=10.1128/aem.70.2.1040-1050.2004;
RA   Gruenberg K., Mueller E.C., Otto A., Reszka R., Linder D., Kube M.,
RA   Reinhardt R., Schueler D.;
RT   "Biochemical and proteomic analysis of the magnetosome membrane in
RT   Magnetospirillum gryphiswaldense.";
RL   Appl. Environ. Microbiol. 70:1040-1050(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 6361 / JCM 21280 / NBRC 15271 / MSR-1;
RX   PubMed=17449609; DOI=10.1128/jb.00119-07;
RA   Richter M., Kube M., Bazylinski D.A., Lombardot T., Gloeckner F.O.,
RA   Reinhardt R., Schueler D.;
RT   "Comparative genome analysis of four magnetotactic bacteria reveals a
RT   complex set of group-specific genes implicated in magnetosome
RT   biomineralization and function.";
RL   J. Bacteriol. 189:4899-4910(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 6361 / JCM 21280 / NBRC 15271 / MSR-1;
RX   PubMed=24625872; DOI=10.1128/genomea.00171-14;
RA   Wang X., Wang Q., Zhang W., Wang Y., Li L., Wen T., Zhang T., Zhang Y.,
RA   Xu J., Hu J., Li S., Liu L., Liu J., Jiang W., Tian J., Li Y., Schuler D.,
RA   Wang L., Li J.;
RT   "Complete genome sequence of Magnetospirillum gryphiswaldense MSR-1.";
RL   Genome Announc. 2:0-0(2014).
CC   -!- SUBCELLULAR LOCATION: Magnetosome membrane
CC       {ECO:0000269|PubMed:14766587}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- MISCELLANEOUS: This bacteria makes up to 60 cubo-octahedral
CC       magnetosomes of about 45 nm in diameter which contain membrane-bound
CC       crystals of magnetite (Fe(3)O(4)). {ECO:0000305}.
CC   -!- MISCELLANEOUS: Does not seem to have an ortholog in most other
CC       magnetotactic bacteria. {ECO:0000305|PubMed:14766587}.
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DR   EMBL; BX640511; CAE45335.1; -; Genomic_DNA.
DR   EMBL; CU459003; CAM75126.1; -; Genomic_DNA.
DR   EMBL; HG794546; CDK98848.1; -; Genomic_DNA.
DR   AlphaFoldDB; V6F2Z8; -.
DR   STRING; 1430440.MGMSRv2_1633; -.
DR   EnsemblBacteria; CDK98848; CDK98848; MGMSRv2__1633.
DR   KEGG; mgy:MGMSRv2__1633; -.
DR   eggNOG; COG3597; Bacteria.
DR   HOGENOM; CLU_076562_1_0_5; -.
DR   Proteomes; UP000018922; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0110146; C:magnetosome membrane; IDA:UniProtKB.
DR   InterPro; IPR021147; DUF697.
DR   Pfam; PF05128; DUF697; 1.
PE   1: Evidence at protein level;
KW   Biomineralization; Direct protein sequencing; Magnetosome; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..195
FT                   /note="Magnetosome membrane protein 22"
FT                   /id="PRO_0000447817"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        10..13
FT                   /note="APAP -> TPAA (in Ref. 1; CAE45335 and 2; CAM75126)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        23..25
FT                   /note="TAG -> AVA (in Ref. 1; CAE45335 and 2; CAM75126)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   195 AA;  19977 MW;  EEC99127BCD7E0EE CRC64;
     MAAQTAASEA PAPAAAPADS PTTAGPTPDS VGRDLVAENM IKDYVLAAVA ASIVPVPLFD
     IAAVVAIELR MIQKLSELYG KPFSESLGRS VIASLAGGVV GYGAGMAVAV SLTKLIPGVG
     WMLGMVSLPV IAGATTYAIG RVFVKHYENG GDIFNLSADA MRAYYKQQFE KGKALAAKVK
     ARKEAAAVDD VAAAH