6PGL_CHLPN
ID 6PGL_CHLPN Reviewed; 258 AA.
AC Q9Z8U5; Q9JSH4; Q9K256;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 132.
DE RecName: Full=6-phosphogluconolactonase;
DE Short=6PGL;
DE EC=3.1.1.31;
GN Name=pgl; Synonyms=devB;
GN OrderedLocusNames=CPn_0239, CP_0523, CPj0239, CpB0245;
OS Chlamydia pneumoniae (Chlamydophila pneumoniae).
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=83558;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CWL029;
RX PubMed=10192388; DOI=10.1038/7716;
RA Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W.,
RA Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
RT "Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
RL Nat. Genet. 21:385-389(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR39;
RX PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O.,
RA Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S.,
RA Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J.,
RA Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G.,
RA Salzberg S.L., Eisen J.A., Fraser C.M.;
RT "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae
RT AR39.";
RL Nucleic Acids Res. 28:1397-1406(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J138;
RX PubMed=10871362; DOI=10.1093/nar/28.12.2311;
RA Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K.,
RA Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
RT "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from
RT Japan and CWL029 from USA.";
RL Nucleic Acids Res. 28:2311-2314(2000).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TW-183;
RA Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P.,
RA Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
RT "The genome sequence of Chlamydia pneumoniae TW183 and comparison with
RT other Chlamydia strains based on whole genome sequence analysis.";
RL Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate
CC + H(+); Xref=Rhea:RHEA:12556, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57955, ChEBI:CHEBI:58759; EC=3.1.1.31;
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step
CC 2/3.
CC -!- SIMILARITY: Belongs to the glucosamine/galactosamine-6-phosphate
CC isomerase family. 6-phosphogluconolactonase subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF73681.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAP98178.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAA98449.1; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AE001363; AAD18392.1; -; Genomic_DNA.
DR EMBL; AE002161; AAF73681.1; ALT_INIT; Genomic_DNA.
DR EMBL; BA000008; BAA98449.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AE009440; AAP98178.1; ALT_INIT; Genomic_DNA.
DR PIR; D72103; D72103.
DR PIR; G86520; G86520.
DR RefSeq; NP_224448.1; NC_000922.1.
DR RefSeq; WP_010882891.1; NZ_LN847257.1.
DR AlphaFoldDB; Q9Z8U5; -.
DR SMR; Q9Z8U5; -.
DR STRING; 115711.CP_0523; -.
DR EnsemblBacteria; AAD18392; AAD18392; CPn_0239.
DR EnsemblBacteria; AAF73681; AAF73681; CP_0523.
DR GeneID; 45050286; -.
DR KEGG; cpa:CP_0523; -.
DR KEGG; cpj:devB; -.
DR KEGG; cpn:CPn_0239; -.
DR KEGG; cpt:CpB0245; -.
DR PATRIC; fig|115713.3.peg.269; -.
DR eggNOG; COG0363; Bacteria.
DR HOGENOM; CLU_053947_2_0_0; -.
DR OrthoDB; 1828393at2; -.
DR UniPathway; UPA00115; UER00409.
DR Proteomes; UP000000583; Chromosome.
DR Proteomes; UP000000801; Chromosome.
DR GO; GO:0017057; F:6-phosphogluconolactonase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR CDD; cd01400; 6PGL; 1.
DR InterPro; IPR005900; 6-phosphogluconolactonase_DevB.
DR InterPro; IPR006148; Glc/Gal-6P_isomerase.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR039104; PGLS.
DR PANTHER; PTHR11054; PTHR11054; 1.
DR Pfam; PF01182; Glucosamine_iso; 1.
DR SUPFAM; SSF100950; SSF100950; 1.
DR TIGRFAMs; TIGR01198; pgl; 1.
PE 3: Inferred from homology;
KW Hydrolase.
FT CHAIN 1..258
FT /note="6-phosphogluconolactonase"
FT /id="PRO_0000090092"
FT CONFLICT 46
FT /note="V -> G (in Ref. 3; BAA98449)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 258 AA; 29334 MW; E49CA50014ECB797 CRC64;
MATLINFNDT NKLLLTKQPS LFIDLASKDW IASANQAIKQ RGAFYVALSG GKTPLEIYKD
IVINKDKLID PSKIFLFWGD ERLAPITSSE SNYGQAMSIL RDLNIPDEQI FRMETENPDG
AKKYQELIEN KIPDASFDMI MLGLGEDGHT LSLFSNTSAL EEENDLVVFN SVPHLETERM
TLTFPCVHKG KHVVVYVQGE NKKPILKSVF FSEGREEKLY PIERVGRDRS PLFWIISPES
YDIADFDNIS SIYKMDIL
