ID   MMPLD_STRCO             Reviewed;         705 AA.
AC   Q9XA86;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Putative membrane protein SCO0839;
GN   OrderedLocusNames=SCO0839; ORFNames=SCF43A.29c;
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA   Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC       (TC 2.A.6) family. MmpL subfamily. {ECO:0000305}.
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DR   EMBL; AL939106; CAB48916.1; -; Genomic_DNA.
DR   PIR; T36452; T36452.
DR   RefSeq; NP_625139.1; NC_003888.3.
DR   RefSeq; WP_011027382.1; NZ_VNID01000004.1.
DR   AlphaFoldDB; Q9XA86; -.
DR   SMR; Q9XA86; -.
DR   STRING; 100226.SCO0839; -.
DR   GeneID; 1096262; -.
DR   KEGG; sco:SCO0839; -.
DR   PATRIC; fig|100226.15.peg.831; -.
DR   eggNOG; COG2409; Bacteria.
DR   HOGENOM; CLU_005108_4_1_11; -.
DR   InParanoid; Q9XA86; -.
DR   OMA; PLYGFVF; -.
DR   PhylomeDB; Q9XA86; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   Pfam; PF03176; MMPL; 2.
DR   PROSITE; PS50156; SSD; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..705
FT                   /note="Putative membrane protein SCO0839"
FT                   /id="PRO_0000103584"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        237..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        281..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        316..336
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        373..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        529..549
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        554..574
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        587..607
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        627..647
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        648..668
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   705 AA;  73317 MW;  DF4C3B77AE2EA2C4 CRC64;
     MSTPSRPFRS PRRARWLVPV LLLLVWLVVG GALGPYAGKL GEVATNDQAS FLPRSAESTR
     VVDAQQAFQQ DETLPVIVVW TADGDGDAAV TAHQQAATRS VAGLEGDPGI VGPASPALPS
     DDGRALQAVV QVEPDLGERL PDVLADIGDA AGQVPGTRAQ LAGPAASQAD LSDAFAGIDG
     LLLAVALITV LVILLLVYRS VLLPLVIILS AVFALALSCA IVYALADRDV VRVDGQVQGI
     LSILVIGAAT DYALLLTARF REELARHPDR FGAVRAALRD SWGAVVASAA TVALGLLALL
     LSDLTNNRAL GPVGAIGIVC SVLSTLTFLP AVLVLLGRAA YWPAKPVRTG DPEAGHRLWH
     RVAALVDRAP RRIWALSLAA LLACAAFAPT LSSKGVPLDE IFVNDTPSVA AQQTLAEHFP
     GGSGNPAVVI AEADRLDPVL RAARDTRGVA SAAPVTDSGR PGAGTPLVVD GRVRIDATLE
     APADSDAAKS TVVRLRAAVH EVSGADALVG GYTAQQYDTQ ETAAEDRTLI VPVVLAIILV
     ILILLLRSLL MPVLLVATVA LNFLATLGVS ALVFTHVFGF SGTDASVPLY GFVFLVALGV
     DYNIFLMSRV REEALRHGVR EGILRGLTAT GGVITSAGVV LAATFAALGV IPLAFLLQIA
     FIVAFGVLLD TLVVRSLLVP ALARDIGAVA WWPGRLGHRT PAGRD