ID   MMPS3_MYCTO             Reviewed;         299 AA.
AC   P9WJT0; L0T944; P65378; Q10390;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Probable transport accessory protein MmpS3;
GN   Name=mmpS3; OrderedLocusNames=MT2254;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the MmpS family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK46540.1; -; Genomic_DNA.
DR   PIR; G70784; G70784.
DR   RefSeq; WP_003411405.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WJT0; -.
DR   EnsemblBacteria; AAK46540; AAK46540; MT2254.
DR   GeneID; 45426174; -.
DR   KEGG; mtc:MT2254; -.
DR   PATRIC; fig|83331.31.peg.2429; -.
DR   HOGENOM; CLU_089277_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.2880; -; 1.
DR   InterPro; IPR008693; MmpS.
DR   InterPro; IPR038468; MmpS_C.
DR   Pfam; PF05423; Mycobact_memb; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..299
FT                   /note="Probable transport accessory protein MmpS3"
FT                   /id="PRO_0000427776"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          128..213
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..24
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        128..144
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        146..164
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        175..208
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   299 AA;  30955 MW;  DBF65DD4D2E8FBD7 CRC64;
     MSGPNPPGRE PDEPESEPVS DTGDERASGN HLPPVAGGGD KLPSDQTGET DAYSRAYSAP
     ESEHVTGGPY VPADLRLYDY DDYEESSDLD DELAAPRWPW VVGVAAIIAA VALVVSVSLL
     VTRPHTSKLA TGDTTSSAPP VQDEITTTKP APPPPPPAPP PTTEIPTATE TQTVTVTPPP
     PPPPATTTAP PPATTTTAAA PPPTTTTPTG PRQVTYSVTG TKAPGDIISV TYVDAAGRRR
     TQHNVYIPWS MTVTPISQSD VGSVEASSLF RVSKLNCSIT TSDGTVLSSN SNDGPQTSC