ID   6PGL_CHLTR              Reviewed;         256 AA.
AC   O84189;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=6-phosphogluconolactonase;
DE            Short=6PGL;
DE            EC=3.1.1.31;
GN   Name=pgl; Synonyms=devB; OrderedLocusNames=CT_186;
OS   Chlamydia trachomatis (strain D/UW-3/Cx).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=272561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D/UW-3/Cx;
RX   PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA   Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA   Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
RT   "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia
RT   trachomatis.";
RL   Science 282:754-759(1998).
CC   -!- FUNCTION: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate
CC         + H(+); Xref=Rhea:RHEA:12556, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57955, ChEBI:CHEBI:58759; EC=3.1.1.31;
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC       ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step
CC       2/3.
CC   -!- SIMILARITY: Belongs to the glucosamine/galactosamine-6-phosphate
CC       isomerase family. 6-phosphogluconolactonase subfamily. {ECO:0000305}.
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DR   EMBL; AE001273; AAC67778.1; -; Genomic_DNA.
DR   PIR; C71546; C71546.
DR   RefSeq; NP_219690.1; NC_000117.1.
DR   RefSeq; WP_009871532.1; NC_000117.1.
DR   AlphaFoldDB; O84189; -.
DR   SMR; O84189; -.
DR   STRING; 813.O172_01005; -.
DR   EnsemblBacteria; AAC67778; AAC67778; CT_186.
DR   GeneID; 884943; -.
DR   KEGG; ctr:CT_186; -.
DR   PATRIC; fig|272561.5.peg.200; -.
DR   HOGENOM; CLU_053947_2_0_0; -.
DR   InParanoid; O84189; -.
DR   OMA; YQLFEFE; -.
DR   UniPathway; UPA00115; UER00409.
DR   Proteomes; UP000000431; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0017057; F:6-phosphogluconolactonase activity; IBA:GO_Central.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0009051; P:pentose-phosphate shunt, oxidative branch; IBA:GO_Central.
DR   CDD; cd01400; 6PGL; 1.
DR   InterPro; IPR005900; 6-phosphogluconolactonase_DevB.
DR   InterPro; IPR006148; Glc/Gal-6P_isomerase.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   InterPro; IPR039104; PGLS.
DR   PANTHER; PTHR11054; PTHR11054; 1.
DR   Pfam; PF01182; Glucosamine_iso; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   TIGRFAMs; TIGR01198; pgl; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..256
FT                   /note="6-phosphogluconolactonase"
FT                   /id="PRO_0000090093"
SQ   SEQUENCE   256 AA;  29014 MW;  CA1D6B5668101BF0 CRC64;
     MATLISLNDA NRMLIADSQE EFLQIACYDW ISTANKAIHK RGAFYVALSG GKTPLQIFQE
     IVKKRAAISD CSKIVVFWGD ERANEDVEAG SNYLKAMDIL KGLRIPEDQI FRMDTADPKG
     DEAYEALIQK YVPDAIFDMV MLGVGEDGHT LSLFPETHAL EEKERFVVFN EVPQLHTRRM
     TLTFPIVRQA RHLVAYVQGE NKQDLFHKLV HPLGRDTFPI ERVGTPLNPV QWVLSSDSCR
     KTDLADIPAD CKLEMF