MMPS4_MYCTO
ID MMPS4_MYCTO Reviewed; 140 AA.
AC P9WJS8; L0T6P9; O53736; P0A5K2;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 35.
DE RecName: Full=Siderophore export accessory protein MmpS4 {ECO:0000250|UniProtKB:P9WJS9};
DE AltName: Full=PGB14T-X;
GN Name=mmpS4; OrderedLocusNames=MT0467;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- FUNCTION: Part of an export system, which is required for biosynthesis
CC and secretion of siderophores. {ECO:0000250|UniProtKB:P9WJS9}.
CC -!- SUBUNIT: Interacts with MmpL4. {ECO:0000250|UniProtKB:P9WJS9}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000250|UniProtKB:P9WJS9}; Single-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the MmpS family. {ECO:0000305}.
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DR EMBL; AE000516; AAK44690.1; -; Genomic_DNA.
DR PIR; D70831; D70831.
DR RefSeq; WP_003402272.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WJS8; -.
DR BMRB; P9WJS8; -.
DR SMR; P9WJS8; -.
DR EnsemblBacteria; AAK44690; AAK44690; MT0467.
DR GeneID; 45424412; -.
DR KEGG; mtc:MT0467; -.
DR PATRIC; fig|83331.31.peg.494; -.
DR HOGENOM; CLU_119497_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.2880; -; 1.
DR InterPro; IPR008693; MmpS.
DR InterPro; IPR038468; MmpS_C.
DR Pfam; PF05423; Mycobact_memb; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..140
FT /note="Siderophore export accessory protein MmpS4"
FT /id="PRO_0000427777"
FT TRANSMEM 2..22
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 140 AA; 15404 MW; 5C94F52A73BEFD53 CRC64;
MLMRTWIPLV ILVVVIVGGF TVHRIRGFFG SENRPSYSDT NLENSKPFNP KHLTYEIFGP
PGTVADISYF DVNSEPQRVD GAVLPWSLHI TTNDAAVMGN IVAQGNSDSI GCRITVDGKV
RAERVSNEVN AYTYCLVKSA