MMPS5_MYCTO
ID MMPS5_MYCTO Reviewed; 142 AA.
AC P9WJS6; L0T4E2; O53785; P65380;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 33.
DE RecName: Full=Siderophore export accessory protein MmpS5 {ECO:0000250|UniProtKB:P9WJS7};
GN Name=mmpS5; OrderedLocusNames=MT0706;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- FUNCTION: Part of an export system, which is required for biosynthesis
CC and secretion of siderophores. {ECO:0000250|UniProtKB:P9WJS7}.
CC -!- SUBUNIT: Interacts with MmpL5. {ECO:0000250|UniProtKB:P9WJS7}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000250|UniProtKB:P9WJS7}; Single-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the MmpS family. {ECO:0000305}.
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DR EMBL; AE000516; AAK44931.1; -; Genomic_DNA.
DR PIR; F70826; F70826.
DR RefSeq; WP_003403439.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WJS6; -.
DR SMR; P9WJS6; -.
DR EnsemblBacteria; AAK44931; AAK44931; MT0706.
DR GeneID; 45424639; -.
DR KEGG; mtc:MT0706; -.
DR PATRIC; fig|83331.31.peg.752; -.
DR HOGENOM; CLU_119497_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.2880; -; 1.
DR InterPro; IPR008693; MmpS.
DR InterPro; IPR038468; MmpS_C.
DR Pfam; PF05423; Mycobact_memb; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..142
FT /note="Siderophore export accessory protein MmpS5"
FT /id="PRO_0000427778"
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 142 AA; 15249 MW; 055BD99A3F46E8F5 CRC64;
MIGTLKRAWI PLLILVVVAI AGFTVQRIRT FFGSEGILVT PKVFADDPEP FDPKVVEYEV
SGSGSYVNIN YLDLDAKPQR IDGAALPWSL TLKTTAPSAA PNILAQGDGT SITCRITVDG
EVKDERTATG VDALTYCFVK SA