MMTA2_MOUSE
ID MMTA2_MOUSE Reviewed; 260 AA.
AC Q99LX5; Q9CSK6;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Multiple myeloma tumor-associated protein 2 homolog;
GN Name=Mmtag2;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-186.
RC STRAIN=C57BL/6J; TISSUE=Embryo;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
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DR EMBL; BC002181; AAH02181.1; -; mRNA.
DR EMBL; AK012628; BAB28366.1; -; mRNA.
DR CCDS; CCDS24764.1; -.
DR RefSeq; NP_077172.1; NM_024210.2.
DR AlphaFoldDB; Q99LX5; -.
DR SMR; Q99LX5; -.
DR BioGRID; 212489; 2.
DR STRING; 10090.ENSMUSP00000020719; -.
DR iPTMnet; Q99LX5; -.
DR PhosphoSitePlus; Q99LX5; -.
DR EPD; Q99LX5; -.
DR jPOST; Q99LX5; -.
DR MaxQB; Q99LX5; -.
DR PaxDb; Q99LX5; -.
DR PeptideAtlas; Q99LX5; -.
DR PRIDE; Q99LX5; -.
DR ProteomicsDB; 295961; -.
DR Antibodypedia; 52229; 72 antibodies from 20 providers.
DR DNASU; 67862; -.
DR Ensembl; ENSMUST00000020719; ENSMUSP00000020719; ENSMUSG00000020441.
DR GeneID; 67862; -.
DR KEGG; mmu:67862; -.
DR UCSC; uc007jdl.1; mouse.
DR MGI; MGI:1915112; 2310033P09Rik.
DR VEuPathDB; HostDB:ENSMUSG00000020441; -.
DR eggNOG; KOG4520; Eukaryota.
DR GeneTree; ENSGT00390000005590; -.
DR HOGENOM; CLU_061193_0_1_1; -.
DR InParanoid; Q99LX5; -.
DR OMA; FTHHKVE; -.
DR OrthoDB; 1325819at2759; -.
DR PhylomeDB; Q99LX5; -.
DR TreeFam; TF332234; -.
DR Reactome; R-MMU-6798695; Neutrophil degranulation.
DR BioGRID-ORCS; 67862; 4 hits in 75 CRISPR screens.
DR PRO; PR:Q99LX5; -.
DR Proteomes; UP000000589; Chromosome 11.
DR RNAct; Q99LX5; protein.
DR Bgee; ENSMUSG00000020441; Expressed in animal zygote and 261 other tissues.
DR Genevisible; Q99LX5; MM.
DR InterPro; IPR019315; MMTA2_N.
DR InterPro; IPR039207; MMTAG2-like.
DR PANTHER; PTHR14580; PTHR14580; 1.
DR Pfam; PF10159; MMtag; 1.
PE 2: Evidence at transcript level;
KW Isopeptide bond; Phosphoprotein; Reference proteome; Ubl conjugation.
FT CHAIN 1..260
FT /note="Multiple myeloma tumor-associated protein 2 homolog"
FT /id="PRO_0000096519"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 146..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..205
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 123
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9BU76"
FT MOD_RES 127
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9BU76"
FT MOD_RES 215
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9BU76"
FT MOD_RES 216
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9BU76"
FT MOD_RES 219
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9BU76"
FT CROSSLNK 22
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q9BU76"
FT CROSSLNK 104
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q9BU76"
FT CROSSLNK 113
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q9BU76"
SQ SEQUENCE 260 AA; 29299 MW; 6D772479E9609AF0 CRC64;
MFGSNRGGVR GGQDQFNWED VKTDKQRENY LGNSLMAPVG RWQKGRDLTW YAKDRAPCTG
PSREEELAAV REAEREALLA ALGYKNVRKQ PTGLSKEDFV EICKREGGDP EEKGVDRLLG
LGSASGSAGR VALSREDKEA AKLGLSVFTH HRVDSEGPST APTAPRKKPR AEDKVEPDAE
SHKKSKKEKK KKKKKHKKHK KKKDKEHKRE ADSCSSSPSP PRPRHQRHSD FSPCSKRKRE
HSQDSGRNPS RRRQDRSSDD
