ID   MNARL_HUMAN             Reviewed;         190 AA.
AC   P59773; H3BM78;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2013, sequence version 2.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Major intrinsically disordered NOTCH2-binding receptor 1-like;
DE   AltName: Full=Membrane integral NOTCH2-associated receptor 2 {ECO:0000312|HGNC:HGNC:33914};
GN   Name=MINAR2 {ECO:0000312|HGNC:HGNC:33914};
GN   Synonyms=KIAA1024L {ECO:0000312|HGNC:HGNC:33914};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A.,
RA   Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R.,
RA   Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L.,
RA   Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N.,
RA   Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J.,
RA   Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A.,
RA   Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MINAR family. {ECO:0000305}.
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DR   EMBL; AC008591; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471062; EAW62380.1; -; Genomic_DNA.
DR   CCDS; CCDS58966.1; -.
DR   RefSeq; NP_001244237.1; NM_001257308.1.
DR   AlphaFoldDB; P59773; -.
DR   STRING; 9606.ENSP00000454268; -.
DR   iPTMnet; P59773; -.
DR   PhosphoSitePlus; P59773; -.
DR   BioMuta; KIAA1024L; -.
DR   DMDM; 519668667; -.
DR   PaxDb; P59773; -.
DR   PeptideAtlas; P59773; -.
DR   PRIDE; P59773; -.
DR   ProteomicsDB; 40832; -.
DR   Antibodypedia; 2707; 6 antibodies from 6 providers.
DR   DNASU; 100127206; -.
DR   Ensembl; ENST00000564719.2; ENSP00000454268.1; ENSG00000186367.7.
DR   GeneID; 100127206; -.
DR   KEGG; hsa:100127206; -.
DR   MANE-Select; ENST00000564719.2; ENSP00000454268.1; NM_001257308.2; NP_001244237.1.
DR   UCSC; uc031skx.2; human.
DR   CTD; 100127206; -.
DR   GeneCards; MINAR2; -.
DR   HGNC; HGNC:33914; MINAR2.
DR   HPA; ENSG00000186367; Tissue enriched (skeletal).
DR   neXtProt; NX_P59773; -.
DR   OpenTargets; ENSG00000186367; -.
DR   VEuPathDB; HostDB:ENSG00000186367; -.
DR   eggNOG; ENOG502RZQB; Eukaryota.
DR   GeneTree; ENSGT00530000063851; -.
DR   HOGENOM; CLU_120056_0_0_1; -.
DR   InParanoid; P59773; -.
DR   OMA; YPAAQHW; -.
DR   OrthoDB; 1321736at2759; -.
DR   PathwayCommons; P59773; -.
DR   BioGRID-ORCS; 100127206; 12 hits in 1057 CRISPR screens.
DR   ChiTaRS; KIAA1024L; human.
DR   Pharos; P59773; Tdark.
DR   PRO; PR:P59773; -.
DR   Proteomes; UP000005640; Chromosome 5.
DR   RNAct; P59773; protein.
DR   Bgee; ENSG00000186367; Expressed in skeletal muscle tissue and 17 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR039706; MINAR1-like.
DR   InterPro; IPR009626; MINAR1-like_C.
DR   PANTHER; PTHR31530; PTHR31530; 1.
DR   Pfam; PF06789; MINAR1_C; 1.
PE   3: Inferred from homology;
KW   Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..190
FT                   /note="Major intrinsically disordered NOTCH2-binding
FT                   receptor 1-like"
FT                   /id="PRO_0000157135"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         79
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8C4X7"
SQ   SEQUENCE   190 AA;  21573 MW;  3BC483841BB66CA5 CRC64;
     MDLSVLPNNN HPDKFLQLDV KSLTRSSALL QASLVRFPGG NYPAAQHWQN LVYSQREKKN
     IAAQRIRGSS ADSLVTADSP PPSMSSVMKN NPLYGDLSLE EAMEERKKNP SWTIEEYDKH
     SLHTNLSGHL KENPNDLRFW LGDMYTPGFD TLLKKEEKQE KHSKFCRMGL ILLVVISILV
     TIVTIITFFT