ID   MNCP_OXYFA              Reviewed;         371 AA.
AC   P15798; O02506; O02594; Q94631;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 2.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Macronuclear solute carrier homolog CR-MSC;
OS   Oxytricha fallax.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX   NCBI_TaxID=5944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SEQUENCE REVISION TO 74-86.
RX   PubMed=8952079; DOI=10.1093/oxfordjournals.molbev.a025581;
RA   Seegmiller A., Williams K.R., Hammersmith R.L., Doak T.G., Witherspoon D.,
RA   Messick T., Storjohann L.L., Herrick G.;
RT   "Internal eliminated sequences interrupting the Oxytricha 81 locus: allelic
RT   divergence, conservation, conversions, and possible transposon origins.";
RL   Mol. Biol. Evol. 13:1351-1362(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 74-371.
RX   PubMed=3123312; DOI=10.1101/gad.1.10.1047;
RA   Herrick G., Hunter D., Williams K., Kotter K.;
RT   "Alternative processing during development of a macronuclear chromosome
RT   family in Oxytricha fallax.";
RL   Genes Dev. 1:1047-1058(1987).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U81495; AAB61089.1; -; Genomic_DNA.
DR   PIR; A28260; A28260.
DR   PIR; T18558; T18558.
DR   AlphaFoldDB; P15798; -.
DR   SMR; P15798; -.
DR   PRIDE; P15798; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.50.40.10; -; 1.
DR   InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR   InterPro; IPR023395; Mt_carrier_dom_sf.
DR   Pfam; PF00153; Mito_carr; 3.
DR   SUPFAM; SSF103506; SSF103506; 1.
DR   PROSITE; PS50920; SOLCAR; 3.
PE   3: Inferred from homology;
KW   Membrane; Repeat; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..371
FT                   /note="Macronuclear solute carrier homolog CR-MSC"
FT                   /id="PRO_0000090709"
FT   TRANSMEM        22..42
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        89..109
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        126..146
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        184..204
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        221..241
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        281..301
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          16..111
FT                   /note="Solcar 1"
FT   REPEAT          120..208
FT                   /note="Solcar 2"
FT   REPEAT          215..304
FT                   /note="Solcar 3"
SQ   SEQUENCE   371 AA;  42618 MW;  5E5F2D73C92D7F9A CRC64;
     MPTQMEVEYW RRRYQRMNYE RFAAANVIAL ITHAATQPLD MVRIRSQMLQ EGKTFSGLGY
     QKGWYPFQIM EEIYAAGGGL RKFYSAFDTF FFRTVCYTTA RVTAFGYFYD KVNKDPRRVA
     RPDFLVAAGV LGGFIAGVVT NPIDIVYNRM QVDELYPQAA RRNYSNTIQG LAKVAEEGAL
     FRGAGANGFK LAAICSSMTN IYDWCKENSY FFFGPHWINR LWGTAVAVAI GTVVSMPFDM
     IRTRLHTMRP LPNGQMPYNG MIDCFNKIIK YECNSKWMSN FGSFYAGGEA YFLRLFLICY
     LSQFLVDYYN ENYYDQEFWQ PQRFHYQSGI DYDIHDPYTD AFNKKLVATY TTATGGMGAA
     HPSGKENLAI I