ID   MND1_BOVIN              Reviewed;         205 AA.
AC   Q32L19;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Meiotic nuclear division protein 1 homolog;
GN   Name=MND1 {ECO:0000250|UniProtKB:Q9BWT6};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1] {ECO:0000312|EMBL:AAI09807.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus {ECO:0000312|EMBL:AAI09807.1};
RC   TISSUE=Liver {ECO:0000312|EMBL:AAI09807.1};
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for proper homologous chromosome pairing and
CC       efficient cross-over and intragenic recombination during meiosis.
CC       Stimulates both DMC1- and RAD51-mediated homologous strand
CC       assimilation, which is required for the resolution of meiotic double-
CC       strand breaks (By similarity). {ECO:0000250|UniProtKB:Q8K396}.
CC   -!- SUBUNIT: Heterodimer with PSMC3IP/HOP2. MND1-PSMC3IP interacts with
CC       DMC1 and RAD51 and binds preferentially to dsDNA (By similarity).
CC       {ECO:0000250|UniProtKB:Q8K396, ECO:0000250|UniProtKB:Q9BWT6}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MND1 family. {ECO:0000305}.
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DR   EMBL; BC109806; AAI09807.1; -; mRNA.
DR   RefSeq; NP_001033312.1; NM_001038223.2.
DR   AlphaFoldDB; Q32L19; -.
DR   SMR; Q32L19; -.
DR   STRING; 9913.ENSBTAP00000000351; -.
DR   PaxDb; Q32L19; -.
DR   GeneID; 618239; -.
DR   KEGG; bta:618239; -.
DR   CTD; 84057; -.
DR   eggNOG; KOG3433; Eukaryota.
DR   InParanoid; Q32L19; -.
DR   OrthoDB; 880961at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IEA:InterPro.
DR   InterPro; IPR040661; LZ3wCH.
DR   InterPro; IPR005647; Mnd1.
DR   InterPro; IPR040453; Mnd1_HTH.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF18517; LZ3wCH; 1.
DR   Pfam; PF03962; Mnd1; 1.
DR   PIRSF; PIRSF026991; Mnd1; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Coiled coil; DNA recombination; DNA-binding; Meiosis; Nucleus;
KW   Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BWT6"
FT   CHAIN           2..205
FT                   /note="Meiotic nuclear division protein 1 homolog"
FT                   /id="PRO_0000318080"
FT   COILED          83..173
FT                   /evidence="ECO:0000255"
FT   MOD_RES         2
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BWT6"
SQ   SEQUENCE   205 AA;  23984 MW;  EC8D6F288212D327 CRC64;
     MSKKKGLSAE EKRTRMMEIF YETKDVFQLK DMEKIAPKEK GITTMSVKEV LQSLVDDGMV
     DCERIGTSNY YWAFPSKALH ARKRKLEVLD SQLSEGNQKY ANLQKSIEKA KVGRHETEER
     TMLAKELSSL RDQREQLKAE VEKYRECDPQ VVEEIRQANQ VAKEAANRWT DNIFAIKSWA
     KRKFGFEENK IDKNFGIPED FDYID