ID   MND1_DANRE              Reviewed;         220 AA.
AC   Q6DC61;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Meiotic nuclear division protein 1 homolog;
GN   Name=mnd1 {ECO:0000250|UniProtKB:Q9BWT6}; ORFNames=zgc:101017;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1] {ECO:0000312|EMBL:AAH78223.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo {ECO:0000312|EMBL:AAH78223.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for proper homologous chromosome pairing and
CC       efficient cross-over and intragenic recombination during meiosis.
CC       Stimulates both DMC1- and RAD51-mediated homologous strand
CC       assimilation, which is required for the resolution of meiotic double-
CC       strand breaks (By similarity). {ECO:0000250|UniProtKB:Q8K396}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MND1 family. {ECO:0000305}.
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DR   EMBL; BC078223; AAH78223.1; -; mRNA.
DR   RefSeq; NP_001003597.1; NM_001003597.2.
DR   AlphaFoldDB; Q6DC61; -.
DR   SMR; Q6DC61; -.
DR   STRING; 7955.ENSDARP00000054264; -.
DR   PaxDb; Q6DC61; -.
DR   Ensembl; ENSDART00000054265; ENSDARP00000054264; ENSDARG00000074451.
DR   GeneID; 445203; -.
DR   KEGG; dre:445203; -.
DR   CTD; 84057; -.
DR   ZFIN; ZDB-GENE-040801-116; mnd1.
DR   eggNOG; KOG3433; Eukaryota.
DR   GeneTree; ENSGT00490000043413; -.
DR   InParanoid; Q6DC61; -.
DR   OrthoDB; 880961at2759; -.
DR   PhylomeDB; Q6DC61; -.
DR   TreeFam; TF314068; -.
DR   PRO; PR:Q6DC61; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 1.
DR   Bgee; ENSDARG00000074451; Expressed in testis and 21 other tissues.
DR   ExpressionAtlas; Q6DC61; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:GO_Central.
DR   InterPro; IPR005647; Mnd1.
DR   InterPro; IPR040453; Mnd1_HTH.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF03962; Mnd1; 1.
DR   PIRSF; PIRSF026991; Mnd1; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; DNA recombination; Meiosis; Nucleus; Reference proteome.
FT   CHAIN           1..220
FT                   /note="Meiotic nuclear division protein 1 homolog"
FT                   /id="PRO_0000318083"
FT   COILED          76..147
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   220 AA;  25176 MW;  90DEAA69311F4BF7 CRC64;
     MSKKKGLSLE EKRSRMMEIF FETKDVFQLK DIEKIAPKSK GITPMSVKEV LQSLVDDNMV
     DTERVGTSNY YWAFPSKALH ARKRRLEELE KQLEDGSQRK KALQQAVDKA KVGREVNEER
     EDLLKELTAL KGQRDQMKVE IEKYQECDPA VVEEIRNANI AAKEAVARWT GGTFGNYLIS
     YLLTCSLTRQ EPWAHHLSPS SGFSPGTACQ TCYYYQQAIS