MND1_DICDI
ID MND1_DICDI Reviewed; 221 AA.
AC Q54E86;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 70.
DE RecName: Full=Meiotic nuclear division protein 1 homolog;
GN Name=mnd1; ORFNames=DDB_G0291750;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- FUNCTION: Required for proper homologous chromosome pairing and
CC efficient cross-over and intragenic recombination. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MND1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAFI02000182; EAL61571.1; -; Genomic_DNA.
DR RefSeq; XP_629976.1; XM_629974.1.
DR AlphaFoldDB; Q54E86; -.
DR SMR; Q54E86; -.
DR STRING; 44689.DDB0302477; -.
DR PaxDb; Q54E86; -.
DR EnsemblProtists; EAL61571; EAL61571; DDB_G0291750.
DR GeneID; 8628306; -.
DR KEGG; ddi:DDB_G0291750; -.
DR dictyBase; DDB_G0291750; mnd1.
DR eggNOG; KOG3433; Eukaryota.
DR HOGENOM; CLU_080628_3_1_1; -.
DR InParanoid; Q54E86; -.
DR OMA; VCYWAFP; -.
DR PhylomeDB; Q54E86; -.
DR PRO; PR:Q54E86; -.
DR Proteomes; UP000002195; Chromosome 6.
DR GO; GO:0000794; C:condensed nuclear chromosome; ISS:dictyBase.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003690; F:double-stranded DNA binding; ISS:dictyBase.
DR GO; GO:0007131; P:reciprocal meiotic recombination; ISS:dictyBase.
DR InterPro; IPR040661; LZ3wCH.
DR InterPro; IPR005647; Mnd1.
DR InterPro; IPR040453; Mnd1_HTH.
DR Pfam; PF18517; LZ3wCH; 1.
DR Pfam; PF03962; Mnd1; 1.
DR PIRSF; PIRSF026991; Mnd1; 1.
PE 3: Inferred from homology;
KW Coiled coil; DNA recombination; Nucleus; Reference proteome.
FT CHAIN 1..221
FT /note="Meiotic nuclear division protein 1 homolog"
FT /id="PRO_0000328308"
FT COILED 89..146
FT /evidence="ECO:0000255"
SQ SEQUENCE 221 AA; 25864 MW; 21A4FE88A02A090C CRC64;
MATRRKGMSP EEKKEKLKEF FHSNSTIYSS KDVESEASKY TGMTQVQCKE TLQMLIDDGV
VNTDKMGSSN FYWSFPSFEF DSKKDKIIEQ TKLLSETKER IQSETKKIEQ LKSERVESET
RTKNLEKLQT LKDDNKSFKE ELLLYADSSL IDDKKRDIKI AIAAVNRYTD NISSLRQFCD
SKYNIRPSDF DTSFGIKPDM DYLEEYNFND TPQPVNKKKR K