ID   MND1_XENLA              Reviewed;         205 AA.
AC   Q5XGY9;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Meiotic nuclear division protein 1 homolog;
GN   Name=mnd1 {ECO:0000250|UniProtKB:Q9BWT6};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1] {ECO:0000312|EMBL:AAH84288.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary {ECO:0000312|EMBL:AAH84288.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for proper homologous chromosome pairing and
CC       efficient cross-over and intragenic recombination during meiosis.
CC       Stimulates both dmc1- and rad51-mediated homologous strand
CC       assimilation, which is required for the resolution of meiotic double-
CC       strand breaks (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MND1 family. {ECO:0000305}.
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DR   EMBL; BC084288; AAH84288.1; -; mRNA.
DR   RefSeq; XP_018086843.1; XM_018231354.1.
DR   AlphaFoldDB; Q5XGY9; -.
DR   SMR; Q5XGY9; -.
DR   BioGRID; 105193; 1.
DR   MaxQB; Q5XGY9; -.
DR   GeneID; 108699336; -.
DR   KEGG; xla:108699336; -.
DR   OMA; VCYWAFP; -.
DR   OrthoDB; 880961at2759; -.
DR   Proteomes; UP000186698; Chromosome 1L.
DR   Bgee; 108699336; Expressed in oocyte and 18 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IEA:InterPro.
DR   InterPro; IPR040661; LZ3wCH.
DR   InterPro; IPR005647; Mnd1.
DR   InterPro; IPR040453; Mnd1_HTH.
DR   Pfam; PF18517; LZ3wCH; 1.
DR   Pfam; PF03962; Mnd1; 1.
DR   PIRSF; PIRSF026991; Mnd1; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; DNA recombination; Meiosis; Nucleus; Reference proteome.
FT   CHAIN           1..205
FT                   /note="Meiotic nuclear division protein 1 homolog"
FT                   /id="PRO_0000318084"
FT   COILED          79..147
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   205 AA;  24022 MW;  2EFE64865708262B CRC64;
     MSKKRGLSVE EKRTRMMEIF FETKDVFQLK DLEKIAPKEK GITSMSVKEI LQSLVDDGMV
     DSERIGTSNY FWAFPSKALH ARKRKLETLE AQFTEVKQKK ESLQQCVDKA KVGRQDTEER
     SKLVEELASL RHRKEELCAD LEKYKECDPD VVEEIRQSNK VAKDAVNRWT DNIFAVKSWA
     KKKFGFEERQ IDKNFGIPED FDYID