MNE1_YEAST
ID MNE1_YEAST Reviewed; 663 AA.
AC P24720; D6W345;
DT 01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 25-MAY-2022, entry version 130.
DE RecName: Full=Protein MNE1;
GN Name=MNE1; Synonyms=MNE; OrderedLocusNames=YOR350C; ORFNames=O6353;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 90843 / S288c / FY73;
RX PubMed=8948102;
RX DOI=10.1002/(sici)1097-0061(199611)12:14<1475::aid-yea32>3.0.co;2-v;
RA Purnelle B., Goffeau A.;
RT "Nucleotide sequence analysis of a 40 kb segment on the right arm of yeast
RT chromosome XV reveals 18 open reading frames including a new pyruvate
RT kinase and three homologues to chromosome I genes.";
RL Yeast 12:1475-1481(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169874;
RA Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J.,
RA Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A.,
RA Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B.,
RA Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H.,
RA Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E.,
RA Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C.,
RA Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G.,
RA Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B.,
RA Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F.,
RA Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E.,
RA Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I.,
RA Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H.,
RA Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL Nature 387:98-102(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-219.
RX PubMed=1741279; DOI=10.1093/nar/20.3.449;
RA Leem S.-H., Ogawa H.;
RT "The MRE4 gene encodes a novel protein kinase homologue required for
RT meiotic recombination in Saccharomyces cerevisiae.";
RL Nucleic Acids Res. 20:449-457(1992).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- MISCELLANEOUS: Present with 861 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; X95720; CAA65037.1; -; Genomic_DNA.
DR EMBL; Z75258; CAA99678.1; -; Genomic_DNA.
DR EMBL; X63112; CAA44826.1; -; Genomic_DNA.
DR EMBL; BK006948; DAA11111.1; -; Genomic_DNA.
DR PIR; S67259; S67259.
DR RefSeq; NP_014995.1; NM_001183770.1.
DR AlphaFoldDB; P24720; -.
DR BioGRID; 34735; 264.
DR DIP; DIP-4059N; -.
DR IntAct; P24720; 1.
DR STRING; 4932.YOR350C; -.
DR MaxQB; P24720; -.
DR PaxDb; P24720; -.
DR PRIDE; P24720; -.
DR EnsemblFungi; YOR350C_mRNA; YOR350C; YOR350C.
DR GeneID; 854532; -.
DR KEGG; sce:YOR350C; -.
DR SGD; S000005877; MNE1.
DR VEuPathDB; FungiDB:YOR350C; -.
DR eggNOG; ENOG502S10A; Eukaryota.
DR HOGENOM; CLU_029218_0_0_1; -.
DR InParanoid; P24720; -.
DR OMA; CLAKFTL; -.
DR PRO; PR:P24720; -.
DR Proteomes; UP000002311; Chromosome XV.
DR RNAct; P24720; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR GO; GO:0005759; C:mitochondrial matrix; IDA:SGD.
DR GO; GO:0005739; C:mitochondrion; HDA:SGD.
DR GO; GO:1990904; C:ribonucleoprotein complex; IDA:SGD.
DR GO; GO:0000372; P:Group I intron splicing; IMP:SGD.
DR GO; GO:0090615; P:mitochondrial mRNA processing; IMP:SGD.
DR InterPro; IPR025694; MNE1.
DR Pfam; PF13762; MNE1; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..663
FT /note="Protein MNE1"
FT /id="PRO_0000096524"
SQ SEQUENCE 663 AA; 77230 MW; 208DD629E7034858 CRC64;
MKLLFKRYSS SHIGKLIKDS LITPEILPQL GRQPSSHKRL PNNKRTNSIT DKWLKDALTR
KDKLNEDKLQ NVNLRLNVVL TTLQKLRTSD NPALYFALLN RIGTGHIKWL NKSGRQIDAF
PPDRLPLEFY HELSNMLYKL SLRSANDKIA LAKFSLQLLD RYYFLKTKSL TIEGKFRANI
KFLRNCTLLI VKSQSNYYLR AIQRLFAENS EGQLLANLSQ LAFYVETSQW TSMLDILSSC
VPDSGLRGSK ERERAIQLLE LFSPCLVKSL KVMIAQNMEN EACQILRSLS EWNFHFDQHD
SSNLIQLSQN HSCLKVIETM NGLSSTTAVT RQFGLEKLPT DVSLKQSIHI LSKDNFEPLK
QDSFLQFLSF KLSDLPLNLE VWKKHIKEVD DQMQAESNLH SLRAFFIDML LCHLSVRKDF
DFMLSLVEHI VYEKNLWQPL LLTDNIVGNK ENSTFHCLFH GASQDISTKL TLLALYNQLN
EIGYQFTSHD FLSMLKVCKN YSDSDFFYFA FYNLLVTQSH KFFLFDKFSD KFSWRLPIQI
GDAISEWLSS LEIDIQENTD RVLQITDDVG EWYVENKPFK SEKGTIQPIN IMELRKIFGE
RKTLFHMDSE IFQKSKAKRD KEMRNEALFT ANDAEYNFAA DVSYAKRVEN LFSYIRSKQM
QQK
