ID   MNHB1_STAAM             Reviewed;         142 AA.
AC   P60676; Q9ZNG5;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   13-APR-2004, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Na(+)/H(+) antiporter subunit B1;
DE   AltName: Full=Mnh complex subunit B1;
GN   Name=mnhB1; OrderedLocusNames=SAV0951;
OS   Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu50 / ATCC 700699;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
CC   -!- FUNCTION: Mnh complex is a Na(+)/H(+) antiporter involved in Na(+)
CC       excretion. {ECO:0000250}.
CC   -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC       subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B
CC       family. {ECO:0000305}.
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DR   EMBL; BA000017; BAB57113.1; -; Genomic_DNA.
DR   RefSeq; WP_001081626.1; NC_002758.2.
DR   AlphaFoldDB; P60676; -.
DR   SMR; P60676; -.
DR   PaxDb; P60676; -.
DR   EnsemblBacteria; BAB57113; BAB57113; SAV0951.
DR   GeneID; 66839149; -.
DR   KEGG; sav:SAV0951; -.
DR   HOGENOM; CLU_101659_1_1_9; -.
DR   OMA; HPGFLMP; -.
DR   PhylomeDB; P60676; -.
DR   BioCyc; SAUR158878:SAV_RS05170-MON; -.
DR   Proteomes; UP000002481; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005281; CPA3_sub_B.
DR   InterPro; IPR007182; MnhB.
DR   Pfam; PF04039; MnhB; 1.
DR   TIGRFAMs; TIGR00943; 2a6301s02; 1.
PE   3: Inferred from homology;
KW   Antiport; Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW   Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..142
FT                   /note="Na(+)/H(+) antiporter subunit B1"
FT                   /id="PRO_0000088857"
FT   TRANSMEM        9..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        70..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   142 AA;  15682 MW;  4BF779759F08D24B CRC64;
     MNRQQNDLIL QFAAVIIFFM VMVFGFSLFL AGHYTPGGGF VGGLLFASSL VIITIAFDIE
     TMRKIFPLDF KILIGIGLVF CIATPIASWF LGKNFFTHVT FDIPLFILEP VHMTTAVFFD
     FGVLCAVVGT VMTIIISIGE NE