ID   MNHB1_STAHJ             Reviewed;         142 AA.
AC   Q4L4W6;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Na(+)/H(+) antiporter subunit B1;
DE   AltName: Full=Mnh complex subunit B1;
GN   Name=mnhB1; OrderedLocusNames=SH2000;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- FUNCTION: Mnh complex is a Na(+)/H(+) antiporter involved in Na(+)
CC       excretion. {ECO:0000250}.
CC   -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC       subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B
CC       family. {ECO:0000305}.
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DR   EMBL; AP006716; BAE05309.1; -; Genomic_DNA.
DR   RefSeq; WP_011276267.1; NC_007168.1.
DR   AlphaFoldDB; Q4L4W6; -.
DR   SMR; Q4L4W6; -.
DR   STRING; 279808.SH2000; -.
DR   EnsemblBacteria; BAE05309; BAE05309; SH2000.
DR   KEGG; sha:SH2000; -.
DR   eggNOG; COG2111; Bacteria.
DR   HOGENOM; CLU_101659_1_1_9; -.
DR   OMA; HPGFLMP; -.
DR   OrthoDB; 1962104at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005281; CPA3_sub_B.
DR   InterPro; IPR007182; MnhB.
DR   Pfam; PF04039; MnhB; 1.
DR   TIGRFAMs; TIGR00943; 2a6301s02; 1.
PE   3: Inferred from homology;
KW   Antiport; Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW   Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..142
FT                   /note="Na(+)/H(+) antiporter subunit B1"
FT                   /id="PRO_0000372115"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   142 AA;  15695 MW;  522F4BFC58488F70 CRC64;
     MNRQNNNLMF QYAAVIIAFL IALFGVTLFF AGHYTPGGGF VGGLLLSCAL TIIAIAFDIK
     TMEKVFPWDF KILIGIGLLF CVATPLASWF YGENFFTHTE FNIPLPLLQP VHMNTPMFFD
     FGVLCAVVGT IMTIIITIGE SE