MNHB2_STAA1
ID MNHB2_STAA1 Reviewed; 141 AA.
AC A7WZ77;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=Putative antiporter subunit mnhB2;
DE AltName: Full=Mrp complex subunit B2;
DE AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhB2;
GN Name=mnhB2; Synonyms=mrpB2; OrderedLocusNames=SAHV_0620;
OS Staphylococcus aureus (strain Mu3 / ATCC 700698).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=418127;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mu3 / ATCC 700698;
RX PubMed=17954695; DOI=10.1128/aac.00534-07;
RA Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K.;
RT "Mutated response regulator graR is responsible for phenotypic conversion
RT of Staphylococcus aureus from heterogeneous vancomycin-intermediate
RT resistance to vancomycin-intermediate resistance.";
RL Antimicrob. Agents Chemother. 52:45-53(2008).
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B
CC family. {ECO:0000305}.
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DR EMBL; AP009324; BAF77503.1; -; Genomic_DNA.
DR RefSeq; WP_000661906.1; NZ_CTYB01000002.1.
DR AlphaFoldDB; A7WZ77; -.
DR SMR; A7WZ77; -.
DR KEGG; saw:SAHV_0620; -.
DR HOGENOM; CLU_101659_1_1_9; -.
DR OMA; FHGDYGP; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR007182; MnhB.
DR Pfam; PF04039; MnhB; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Ion transport; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..141
FT /note="Putative antiporter subunit mnhB2"
FT /id="PRO_0000372273"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 114..134
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 141 AA; 15455 MW; EFE7E13047859A26 CRC64;
MKENDVVLRT VTKLVVFILL TFGFYVFFAG HNNPGGGFIG GLIFSSAFIL MFLAFNVEEV
LESLPIDFRI LMIIGALVSS ITAIIPMFFG KPFLSQYETT WILPILGQIH VSTITLFELG
ILFSVVGVIV TVMLSLSGGR S