MNHB2_STAAM
ID MNHB2_STAAM Reviewed; 141 AA.
AC Q99VZ1;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Putative antiporter subunit mnhB2;
DE AltName: Full=Mrp complex subunit B2;
DE AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhB2;
GN Name=mnhB2; Synonyms=mrpB2; OrderedLocusNames=SAV0623;
OS Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=158878;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mu50 / ATCC 700699;
RX PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA Hiramatsu K.;
RT "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL Lancet 357:1225-1240(2001).
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B
CC family. {ECO:0000305}.
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DR EMBL; BA000017; BAB56785.1; -; Genomic_DNA.
DR RefSeq; WP_000661906.1; NC_002758.2.
DR AlphaFoldDB; Q99VZ1; -.
DR SMR; Q99VZ1; -.
DR PaxDb; Q99VZ1; -.
DR EnsemblBacteria; BAB56785; BAB56785; SAV0623.
DR KEGG; sav:SAV0623; -.
DR HOGENOM; CLU_101659_1_1_9; -.
DR OMA; FHGDYGP; -.
DR PhylomeDB; Q99VZ1; -.
DR BioCyc; SAUR158878:SAV_RS03445-MON; -.
DR Proteomes; UP000002481; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR007182; MnhB.
DR Pfam; PF04039; MnhB; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Ion transport; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..141
FT /note="Putative antiporter subunit mnhB2"
FT /id="PRO_0000372274"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 114..134
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 141 AA; 15455 MW; EFE7E13047859A26 CRC64;
MKENDVVLRT VTKLVVFILL TFGFYVFFAG HNNPGGGFIG GLIFSSAFIL MFLAFNVEEV
LESLPIDFRI LMIIGALVSS ITAIIPMFFG KPFLSQYETT WILPILGQIH VSTITLFELG
ILFSVVGVIV TVMLSLSGGR S