ID   MNHB2_STAES             Reviewed;         141 AA.
AC   Q8CQ49;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Putative antiporter subunit mnhB2;
DE   AltName: Full=Mrp complex subunit B2;
DE   AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhB2;
GN   Name=mnhB2; Synonyms=mrpB2; OrderedLocusNames=SE_0398;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC       subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B
CC       family. {ECO:0000305}.
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DR   EMBL; AE015929; AAO03995.1; -; Genomic_DNA.
DR   RefSeq; NP_763953.1; NC_004461.1.
DR   RefSeq; WP_001832105.1; NZ_WBME01000020.1.
DR   AlphaFoldDB; Q8CQ49; -.
DR   SMR; Q8CQ49; -.
DR   STRING; 176280.SE_0398; -.
DR   EnsemblBacteria; AAO03995; AAO03995; SE_0398.
DR   GeneID; 50019445; -.
DR   KEGG; sep:SE_0398; -.
DR   PATRIC; fig|176280.10.peg.372; -.
DR   eggNOG; COG2111; Bacteria.
DR   HOGENOM; CLU_101659_1_1_9; -.
DR   OMA; FHGDYGP; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR007182; MnhB.
DR   Pfam; PF04039; MnhB; 1.
PE   3: Inferred from homology;
KW   Antiport; Cell membrane; Ion transport; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..141
FT                   /note="Putative antiporter subunit mnhB2"
FT                   /id="PRO_0000372281"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   141 AA;  15251 MW;  58730FF8C9B5FB62 CRC64;
     MKENDVVLKS VTKIVVFILL TFGFYVFFAG HNNPGGGFIG GLIFSSAFIL MFLAFDVNEV
     LKSLPIDFKK LMIIGSLISV ATASVPMFFG KPFLYQTEAN VTFPLLGHVH VTTVTLFELG
     ILLTVVGVIV TVMLSISGGR S