MNHB2_STAS1
ID MNHB2_STAS1 Reviewed; 141 AA.
AC Q49VH0;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 13-SEP-2005, sequence version 1.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=Putative antiporter subunit mnhB2;
DE AltName: Full=Mrp complex subunit B2;
DE AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhB2;
GN Name=mnhB2; Synonyms=mrpB2; OrderedLocusNames=SSP2095;
OS Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM
OS 20229 / NCIMB 8711 / NCTC 7292 / S-41).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=342451;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41;
RX PubMed=16135568; DOI=10.1073/pnas.0502950102;
RA Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M.,
RA Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.;
RT "Whole genome sequence of Staphylococcus saprophyticus reveals the
RT pathogenesis of uncomplicated urinary tract infection.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005).
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B
CC family. {ECO:0000305}.
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DR EMBL; AP008934; BAE19240.1; -; Genomic_DNA.
DR RefSeq; WP_011303737.1; NZ_MTGA01000039.1.
DR AlphaFoldDB; Q49VH0; -.
DR SMR; Q49VH0; -.
DR STRING; 342451.SSP2095; -.
DR PRIDE; Q49VH0; -.
DR EnsemblBacteria; BAE19240; BAE19240; SSP2095.
DR GeneID; 66868252; -.
DR KEGG; ssp:SSP2095; -.
DR eggNOG; COG2111; Bacteria.
DR HOGENOM; CLU_101659_1_1_9; -.
DR OMA; FHGDYGP; -.
DR OrthoDB; 1962104at2; -.
DR Proteomes; UP000006371; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR007182; MnhB.
DR Pfam; PF04039; MnhB; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Ion transport; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..141
FT /note="Putative antiporter subunit mnhB2"
FT /id="PRO_0000372284"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 116..136
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 141 AA; 15224 MW; F36170CA0BC2A7B5 CRC64;
MKENDVVLKT VTKIVVFILL TFGFYLFLAG HNNPGGGFIG GLVFSSAFLL MFLAFDVKQV
LVALPLDFRI LMICGSLLSF LTAVVPMFFG KPFLYQTDAY VQLPLLGEVH LTTVTVFEAG
IVLAVVGVVV TVMLSISGGR S