MNHC2_STAAB
ID MNHC2_STAAB Reviewed; 114 AA.
AC Q2YSV5;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=Putative antiporter subunit mnhC2;
DE AltName: Full=Mrp complex subunit C2;
DE AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhC2;
GN Name=mnhC2; Synonyms=mrpC2; OrderedLocusNames=SAB0575;
OS Staphylococcus aureus (strain bovine RF122 / ET3-1).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=273036;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bovine RF122 / ET3-1;
RX PubMed=17971880; DOI=10.1371/journal.pone.0001120;
RA Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.;
RT "Molecular correlates of host specialization in Staphylococcus aureus.";
RL PLoS ONE 2:E1120-E1120(2007).
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C
CC family. {ECO:0000305}.
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DR EMBL; AJ938182; CAI80263.1; -; Genomic_DNA.
DR RefSeq; WP_001048985.1; NC_007622.1.
DR AlphaFoldDB; Q2YSV5; -.
DR SMR; Q2YSV5; -.
DR KEGG; sab:SAB0575; -.
DR HOGENOM; CLU_082058_3_1_9; -.
DR OMA; AIYMMLR; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR039428; NUOK/Mnh_C1-like.
DR Pfam; PF00420; Oxidored_q2; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Ion transport; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..114
FT /note="Putative antiporter subunit mnhC2"
FT /id="PRO_0000372248"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 114 AA; 12496 MW; 530D8DC7C28622BC CRC64;
MNLILLLVIG FLVFIGTYMI LSINLIRIVI GISIYTHAGN LIIMSMGTYG SSRSEPLITG
GNQLFVDPLL QAIVLTAIVI GFGMTAFLLV LVYRTYKVTK EDEIEGLRGE DDAK