MNHC2_STAAN
ID MNHC2_STAAN Reviewed; 114 AA.
AC Q7A726;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=Putative antiporter subunit mnhC2;
DE AltName: Full=Mrp complex subunit C2;
DE AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhC2;
GN Name=mnhC2; Synonyms=mrpC2; OrderedLocusNames=SA0580;
OS Staphylococcus aureus (strain N315).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=158879;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N315;
RX PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA Hiramatsu K.;
RT "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL Lancet 357:1225-1240(2001).
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C
CC family. {ECO:0000305}.
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DR EMBL; BA000018; BAB41812.1; -; Genomic_DNA.
DR PIR; A89832; A89832.
DR RefSeq; WP_001048985.1; NC_002745.2.
DR AlphaFoldDB; Q7A726; -.
DR SMR; Q7A726; -.
DR EnsemblBacteria; BAB41812; BAB41812; BAB41812.
DR KEGG; sau:SA0580; -.
DR HOGENOM; CLU_082058_3_1_9; -.
DR OMA; AIYMMLR; -.
DR Proteomes; UP000000751; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR039428; NUOK/Mnh_C1-like.
DR Pfam; PF00420; Oxidored_q2; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Ion transport; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..114
FT /note="Putative antiporter subunit mnhC2"
FT /id="PRO_0000372257"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 114 AA; 12496 MW; 530D8DC7C28622BC CRC64;
MNLILLLVIG FLVFIGTYMI LSINLIRIVI GISIYTHAGN LIIMSMGTYG SSRSEPLITG
GNQLFVDPLL QAIVLTAIVI GFGMTAFLLV LVYRTYKVTK EDEIEGLRGE DDAK