MNHC2_STAHJ
ID MNHC2_STAHJ Reviewed; 116 AA.
AC Q4L445;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 02-AUG-2005, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Putative antiporter subunit mnhC2;
DE AltName: Full=Mrp complex subunit C2;
DE AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhC2;
GN Name=mnhC2; Synonyms=mrpC2; OrderedLocusNames=SH2273;
OS Staphylococcus haemolyticus (strain JCSC1435).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=279808;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCSC1435;
RX PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA Hiramatsu K.;
RT "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT extreme plasticity of its genome and the evolution of human-colonizing
RT staphylococcal species.";
RL J. Bacteriol. 187:7292-7308(2005).
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C
CC family. {ECO:0000305}.
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DR EMBL; AP006716; BAE05582.1; -; Genomic_DNA.
DR RefSeq; WP_011276532.1; NC_007168.1.
DR AlphaFoldDB; Q4L445; -.
DR SMR; Q4L445; -.
DR STRING; 279808.SH2273; -.
DR EnsemblBacteria; BAE05582; BAE05582; SH2273.
DR GeneID; 58061607; -.
DR KEGG; sha:SH2273; -.
DR eggNOG; COG1006; Bacteria.
DR HOGENOM; CLU_082058_3_1_9; -.
DR OMA; AIYMMLR; -.
DR OrthoDB; 2078994at2; -.
DR Proteomes; UP000000543; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR039428; NUOK/Mnh_C1-like.
DR Pfam; PF00420; Oxidored_q2; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Ion transport; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..116
FT /note="Putative antiporter subunit mnhC2"
FT /id="PRO_0000372264"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 116 AA; 13001 MW; 24568E88BCEC64BF CRC64;
MNLILLLVIG FLVFIGTYMI LSLNLIRIVI GISIYTHAGN LIIMSMGHYS NKMTEPLIHG
SNTNYVDPLL QAIVLTAIVI GFAMTAFLLV LVYRTYRVTK EANIDVLRGE EDENEQ