MNHE2_STAAB
ID MNHE2_STAAB Reviewed; 160 AA.
AC Q2YSV3;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Putative antiporter subunit mnhE2;
DE AltName: Full=Mrp complex subunit E2;
DE AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhE2;
GN Name=mnhE2; Synonyms=mrpE2; OrderedLocusNames=SAB0577;
OS Staphylococcus aureus (strain bovine RF122 / ET3-1).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=273036;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bovine RF122 / ET3-1;
RX PubMed=17971880; DOI=10.1371/journal.pone.0001120;
RA Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.;
RT "Molecular correlates of host specialization in Staphylococcus aureus.";
RL PLoS ONE 2:E1120-E1120(2007).
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E
CC family. {ECO:0000305}.
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DR EMBL; AJ938182; CAI80265.1; -; Genomic_DNA.
DR RefSeq; WP_001071971.1; NC_007622.1.
DR AlphaFoldDB; Q2YSV3; -.
DR SMR; Q2YSV3; -.
DR KEGG; sab:SAB0577; -.
DR HOGENOM; CLU_086615_3_2_9; -.
DR OMA; YSRRIPR; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002758; Cation_antiport_E.
DR PANTHER; PTHR34584; PTHR34584; 1.
DR Pfam; PF01899; MNHE; 1.
DR PIRSF; PIRSF019239; MrpE; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Ion transport; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..160
FT /note="Putative antiporter subunit mnhE2"
FT /id="PRO_0000372210"
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 160 AA; 18835 MW; 9E8891750A665B56 CRC64;
MNQIVLNIII AFLWVLFQDE DHFKFSTFFS GYLIGLIVIY ILHRFFSDDF YVRKIWVAIK
FLGVYLYQLI TSSISTINYI LFKTKDMNPG LLSYETRLTS DWAITFLTIL IIITPGSTVI
RISQDSKKFF IHSIDVSEKE KDSLLRSIKH YEDLILEVSR