MNHF2_STAA8
ID MNHF2_STAA8 Reviewed; 100 AA.
AC P0C948;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 1.
DT 25-MAY-2022, entry version 39.
DE RecName: Full=Putative antiporter subunit mnhF2;
DE AltName: Full=Mrp complex subunit F2;
DE AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhF2;
GN Name=mnhF2; Synonyms=mrpF2; OrderedLocusNames=SAOUHSC_00630.1;
OS Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=93061;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 8325 / PS 47;
RA Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT "The Staphylococcus aureus NCTC 8325 genome.";
RL (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL D.C. (2006).
RN [2]
RP IDENTIFICATION.
RA Ossandon F.J., Rivera G., Holmes D.S.;
RL Unpublished observations (JUL-2008).
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F
CC family. {ECO:0000305}.
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DR EMBL; CP000253; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; WP_000616642.1; NZ_LS483365.1.
DR AlphaFoldDB; P0C948; -.
DR SMR; P0C948; -.
DR STRING; 1280.SAXN108_0694; -.
DR eggNOG; COG2212; Bacteria.
DR Proteomes; UP000008816; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015385; F:sodium:proton antiporter activity; IBA:GO_Central.
DR InterPro; IPR007208; MrpF/PhaF-like.
DR PANTHER; PTHR34702; PTHR34702; 1.
DR Pfam; PF04066; MrpF_PhaF; 1.
DR PIRSF; PIRSF028784; MrpF; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Ion transport; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..100
FT /note="Putative antiporter subunit mnhF2"
FT /id="PRO_0000372201"
FT TRANSMEM 5..25
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 38..60
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..92
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 100 AA; 10730 MW; 014CDCD636D452CF CRC64;
MIQTITHIMI ISSLIIFGIA LIICLFRLIK GPTTADRVVT FDTTSAVVMS IVGVLSVLMG
TVSFLDSIML IAIISFVSSV SISRFIGGGH VFNGNNKRNL