ID   MNHF2_STAAT             Reviewed;         100 AA.
AC   A8Z149;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Putative antiporter subunit mnhF2;
DE   AltName: Full=Mrp complex subunit F2;
DE   AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhF2;
GN   Name=mnhF2; Synonyms=mrpF2; OrderedLocusNames=USA300HOU_0648;
OS   Staphylococcus aureus (strain USA300 / TCH1516).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=451516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USA300 / TCH1516;
RX   PubMed=17986343; DOI=10.1186/1471-2180-7-99;
RA   Highlander S.K., Hulten K.G., Qin X., Jiang H., Yerrapragada S.,
RA   Mason E.O. Jr., Shang Y., Williams T.M., Fortunov R.M., Liu Y., Igboeli O.,
RA   Petrosino J., Tirumalai M., Uzman A., Fox G.E., Cardenas A.M., Muzny D.M.,
RA   Hemphill L., Ding Y., Dugan S., Blyth P.R., Buhay C.J., Dinh H.H.,
RA   Hawes A.C., Holder M., Kovar C.L., Lee S.L., Liu W., Nazareth L.V.,
RA   Wang Q., Zhou J., Kaplan S.L., Weinstock G.M.;
RT   "Subtle genetic changes enhance virulence of methicillin resistant and
RT   sensitive Staphylococcus aureus.";
RL   BMC Microbiol. 7:99-99(2007).
CC   -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC       subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F
CC       family. {ECO:0000305}.
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DR   EMBL; CP000730; ABX28670.1; -; Genomic_DNA.
DR   RefSeq; WP_000616642.1; NC_010079.1.
DR   AlphaFoldDB; A8Z149; -.
DR   SMR; A8Z149; -.
DR   KEGG; sax:USA300HOU_0648; -.
DR   HOGENOM; CLU_125825_1_3_9; -.
DR   OMA; YERAIYI; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015075; F:ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR007208; MrpF/PhaF-like.
DR   PANTHER; PTHR34702; PTHR34702; 1.
DR   Pfam; PF04066; MrpF_PhaF; 1.
DR   PIRSF; PIRSF028784; MrpF; 1.
PE   3: Inferred from homology;
KW   Antiport; Cell membrane; Ion transport; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..100
FT                   /note="Putative antiporter subunit mnhF2"
FT                   /id="PRO_0000372203"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        70..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   100 AA;  10730 MW;  014CDCD636D452CF CRC64;
     MIQTITHIMI ISSLIIFGIA LIICLFRLIK GPTTADRVVT FDTTSAVVMS IVGVLSVLMG
     TVSFLDSIML IAIISFVSSV SISRFIGGGH VFNGNNKRNL