MNHF2_STAAW
ID MNHF2_STAAW Reviewed; 100 AA.
AC Q7A1M9;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Putative antiporter subunit mnhF2;
DE AltName: Full=Mrp complex subunit F2;
DE AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhF2;
GN Name=mnhF2; Synonyms=mrpF2; OrderedLocusNames=MW0590;
OS Staphylococcus aureus (strain MW2).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=196620;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MW2;
RX PubMed=12044378; DOI=10.1016/s0140-6736(02)08713-5;
RA Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y.,
RA Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
RT "Genome and virulence determinants of high virulence community-acquired
RT MRSA.";
RL Lancet 359:1819-1827(2002).
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F
CC family. {ECO:0000305}.
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DR EMBL; BA000033; BAB94455.1; -; Genomic_DNA.
DR RefSeq; WP_000616642.1; NC_003923.1.
DR AlphaFoldDB; Q7A1M9; -.
DR SMR; Q7A1M9; -.
DR EnsemblBacteria; BAB94455; BAB94455; BAB94455.
DR KEGG; sam:MW0590; -.
DR HOGENOM; CLU_125825_1_3_9; -.
DR OMA; YERAIYI; -.
DR Proteomes; UP000000418; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0015075; F:ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR007208; MrpF/PhaF-like.
DR PANTHER; PTHR34702; PTHR34702; 1.
DR Pfam; PF04066; MrpF_PhaF; 1.
DR PIRSF; PIRSF028784; MrpF; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Ion transport; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..100
FT /note="Putative antiporter subunit mnhF2"
FT /id="PRO_0000372199"
FT TRANSMEM 5..25
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 38..60
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..92
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 100 AA; 10730 MW; 014CDCD636D452CF CRC64;
MIQTITHIMI ISSLIIFGIA LIICLFRLIK GPTTADRVVT FDTTSAVVMS IVGVLSVLMG
TVSFLDSIML IAIISFVSSV SISRFIGGGH VFNGNNKRNL