MNHF2_STAEQ
ID MNHF2_STAEQ Reviewed; 100 AA.
AC Q5HRA7;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Putative antiporter subunit mnhF2;
DE AltName: Full=Mrp complex subunit F2;
DE AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhF2;
GN Name=mnhF2; Synonyms=mrpF2; OrderedLocusNames=SERP0286;
OS Staphylococcus epidermidis (strain ATCC 35984 / RP62A).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=176279;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35984 / RP62A;
RX PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA Fraser C.M.;
RT "Insights on evolution of virulence and resistance from the complete genome
RT analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT strain.";
RL J. Bacteriol. 187:2426-2438(2005).
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F
CC family. {ECO:0000305}.
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DR EMBL; CP000029; AAW53737.1; -; Genomic_DNA.
DR RefSeq; WP_001832031.1; NC_002976.3.
DR AlphaFoldDB; Q5HRA7; -.
DR SMR; Q5HRA7; -.
DR STRING; 176279.SERP0286; -.
DR EnsemblBacteria; AAW53737; AAW53737; SERP0286.
DR GeneID; 50019441; -.
DR KEGG; ser:SERP0286; -.
DR eggNOG; COG2212; Bacteria.
DR HOGENOM; CLU_125825_1_3_9; -.
DR OMA; YERAIYI; -.
DR OrthoDB; 2083248at2; -.
DR Proteomes; UP000000531; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0015075; F:ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR007208; MrpF/PhaF-like.
DR PANTHER; PTHR34702; PTHR34702; 1.
DR Pfam; PF04066; MrpF_PhaF; 1.
DR PIRSF; PIRSF028784; MrpF; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Ion transport; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..100
FT /note="Putative antiporter subunit mnhF2"
FT /id="PRO_0000372206"
FT TRANSMEM 5..25
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 38..60
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..87
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 100 AA; 10943 MW; 4C3A1BDEAEA23540 CRC64;
MIEMFTQIFI ISALVIFGMA LLVCLVRLIK GPTTADRVVS FDASSAVVMS IVGVMSVIFN
SVSYLDSIML IAIISFVSSV SISRFIGEGR VFNGNHKRHR