ID   MNHG1_STAA3             Reviewed;         118 AA.
AC   Q2FIC9;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Na(+)/H(+) antiporter subunit G1;
DE   AltName: Full=Mnh complex subunit G1;
GN   Name=mnhG1; OrderedLocusNames=SAUSA300_0849;
OS   Staphylococcus aureus (strain USA300).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=367830;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USA300;
RX   PubMed=16517273; DOI=10.1016/s0140-6736(06)68231-7;
RA   Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA   Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA   Perdreau-Remington F.;
RT   "Complete genome sequence of USA300, an epidemic clone of community-
RT   acquired meticillin-resistant Staphylococcus aureus.";
RL   Lancet 367:731-739(2006).
CC   -!- FUNCTION: Mnh complex is a Na(+)/H(+) antiporter involved in Na(+)
CC       excretion. {ECO:0000250}.
CC   -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC       subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G
CC       family. {ECO:0000305}.
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DR   EMBL; CP000255; ABD22142.1; -; Genomic_DNA.
DR   RefSeq; WP_000590451.1; NZ_CP027476.1.
DR   AlphaFoldDB; Q2FIC9; -.
DR   SMR; Q2FIC9; -.
DR   EnsemblBacteria; ABD22142; ABD22142; SAUSA300_0849.
DR   KEGG; saa:SAUSA300_0849; -.
DR   HOGENOM; CLU_121334_0_3_9; -.
DR   OMA; TNPISAH; -.
DR   Proteomes; UP000001939; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005451; F:monovalent cation:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0098662; P:inorganic cation transmembrane transport; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005133; PhaG_MnhG_YufB.
DR   PANTHER; PTHR34703; PTHR34703; 1.
DR   Pfam; PF03334; PhaG_MnhG_YufB; 1.
DR   TIGRFAMs; TIGR01300; CPA3_mnhG_phaG; 1.
PE   3: Inferred from homology;
KW   Antiport; Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW   Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..118
FT                   /note="Na(+)/H(+) antiporter subunit G1"
FT                   /id="PRO_0000372168"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   118 AA;  12819 MW;  51763F14B3263991 CRC64;
     MIKIILISLA LIFVIIGALI SALAAIGLLR LEDVYSRAHA AGKASTLGAM SLLFGTFLYF
     IATQGFVNMQ LIVAIIFVLI TGPLSSHMIM KAAYNIKTPY TKKTKVDEIS EDLKDTKL