MNHG1_STAAW
ID MNHG1_STAAW Reviewed; 118 AA.
AC P60699; Q9ZNG0;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 13-APR-2004, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Na(+)/H(+) antiporter subunit G1;
DE AltName: Full=Mnh complex subunit G1;
GN Name=mnhG1; OrderedLocusNames=MW0828;
OS Staphylococcus aureus (strain MW2).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=196620;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MW2;
RX PubMed=12044378; DOI=10.1016/s0140-6736(02)08713-5;
RA Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y.,
RA Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
RT "Genome and virulence determinants of high virulence community-acquired
RT MRSA.";
RL Lancet 359:1819-1827(2002).
CC -!- FUNCTION: Mnh complex is a Na(+)/H(+) antiporter involved in Na(+)
CC excretion. {ECO:0000250}.
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G
CC family. {ECO:0000305}.
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DR EMBL; BA000033; BAB94693.1; -; Genomic_DNA.
DR PIR; C89861; C89861.
DR RefSeq; WP_000590451.1; NC_003923.1.
DR AlphaFoldDB; P60699; -.
DR SMR; P60699; -.
DR EnsemblBacteria; BAB94693; BAB94693; BAB94693.
DR KEGG; sam:MW0828; -.
DR HOGENOM; CLU_121334_0_3_9; -.
DR OMA; TNPISAH; -.
DR Proteomes; UP000000418; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005451; F:monovalent cation:proton antiporter activity; IEA:InterPro.
DR GO; GO:0098662; P:inorganic cation transmembrane transport; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR005133; PhaG_MnhG_YufB.
DR PANTHER; PTHR34703; PTHR34703; 1.
DR Pfam; PF03334; PhaG_MnhG_YufB; 1.
DR TIGRFAMs; TIGR01300; CPA3_mnhG_phaG; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..118
FT /note="Na(+)/H(+) antiporter subunit G1"
FT /id="PRO_0000086862"
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 44..66
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 71..90
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 118 AA; 12819 MW; 51763F14B3263991 CRC64;
MIKIILISLA LIFVIIGALI SALAAIGLLR LEDVYSRAHA AGKASTLGAM SLLFGTFLYF
IATQGFVNMQ LIVAIIFVLI TGPLSSHMIM KAAYNIKTPY TKKTKVDEIS EDLKDTKL