ID   MNHG1_STAEQ             Reviewed;         118 AA.
AC   Q5HQL6;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Na(+)/H(+) antiporter subunit G1;
DE   AltName: Full=Mnh complex subunit G1;
GN   Name=mnhG1; OrderedLocusNames=SERP0532;
OS   Staphylococcus epidermidis (strain ATCC 35984 / RP62A).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35984 / RP62A;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- FUNCTION: Mnh complex is a Na(+)/H(+) antiporter involved in Na(+)
CC       excretion. {ECO:0000250}.
CC   -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC       subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000029; AAW53928.1; -; Genomic_DNA.
DR   RefSeq; WP_001831900.1; NC_002976.3.
DR   AlphaFoldDB; Q5HQL6; -.
DR   SMR; Q5HQL6; -.
DR   STRING; 176279.SERP0532; -.
DR   EnsemblBacteria; AAW53928; AAW53928; SERP0532.
DR   GeneID; 50019213; -.
DR   KEGG; ser:SERP0532; -.
DR   eggNOG; COG1320; Bacteria.
DR   HOGENOM; CLU_121334_0_3_9; -.
DR   OMA; TNPISAH; -.
DR   OrthoDB; 2051355at2; -.
DR   Proteomes; UP000000531; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005451; F:monovalent cation:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0098662; P:inorganic cation transmembrane transport; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005133; PhaG_MnhG_YufB.
DR   PANTHER; PTHR34703; PTHR34703; 1.
DR   Pfam; PF03334; PhaG_MnhG_YufB; 1.
DR   TIGRFAMs; TIGR01300; CPA3_mnhG_phaG; 1.
PE   3: Inferred from homology;
KW   Antiport; Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW   Reference proteome; Sodium; Sodium transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..118
FT                   /note="Na(+)/H(+) antiporter subunit G1"
FT                   /id="PRO_0000372170"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   118 AA;  12875 MW;  4AC01F5F7E1358DC CRC64;
     MIATIVTSVS IIFVVLGALI SAFAATGLIR LRDVYSRAHA AGKAATLGAM FLLFGAFLYF
     IGTEGYVNMQ LIIGIIFVFI TGPLSSHLIM KAAYNIKTPY TKDTKIDEIK EDMKHTKL