MNHG1_STAS1
ID MNHG1_STAS1 Reviewed; 118 AA.
AC Q49W85;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 13-SEP-2005, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Na(+)/H(+) antiporter subunit G1;
DE AltName: Full=Mnh complex subunit G1;
GN Name=mnhG1; OrderedLocusNames=SSP1829;
OS Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM
OS 20229 / NCIMB 8711 / NCTC 7292 / S-41).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=342451;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41;
RX PubMed=16135568; DOI=10.1073/pnas.0502950102;
RA Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M.,
RA Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.;
RT "Whole genome sequence of Staphylococcus saprophyticus reveals the
RT pathogenesis of uncomplicated urinary tract infection.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005).
CC -!- FUNCTION: Mnh complex is a Na(+)/H(+) antiporter involved in Na(+)
CC excretion. {ECO:0000250}.
CC -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G
CC family. {ECO:0000305}.
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DR EMBL; AP008934; BAE18974.1; -; Genomic_DNA.
DR RefSeq; WP_011303519.1; NZ_MTGA01000039.1.
DR AlphaFoldDB; Q49W85; -.
DR SMR; Q49W85; -.
DR STRING; 342451.SSP1829; -.
DR EnsemblBacteria; BAE18974; BAE18974; SSP1829.
DR KEGG; ssp:SSP1829; -.
DR PATRIC; fig|342451.11.peg.1825; -.
DR eggNOG; COG1320; Bacteria.
DR HOGENOM; CLU_121334_0_3_9; -.
DR OMA; TNPISAH; -.
DR OrthoDB; 2051355at2; -.
DR Proteomes; UP000006371; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005451; F:monovalent cation:proton antiporter activity; IEA:InterPro.
DR GO; GO:0098662; P:inorganic cation transmembrane transport; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR005133; PhaG_MnhG_YufB.
DR PANTHER; PTHR34703; PTHR34703; 1.
DR Pfam; PF03334; PhaG_MnhG_YufB; 1.
DR TIGRFAMs; TIGR01300; CPA3_mnhG_phaG; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Hydrogen ion transport; Ion transport; Membrane;
KW Reference proteome; Sodium; Sodium transport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..118
FT /note="Na(+)/H(+) antiporter subunit G1"
FT /id="PRO_0000372172"
FT TRANSMEM 9..29
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 118 AA; 12656 MW; F01D9039088B8E02 CRC64;
MITTIVISIA LILVIIGSLI SALAAIGILR LDDVYARAHA AGKAATLGAM LLISGVFLFF
IGREGYVNMQ LIVGILFILI TGPLASHLII KSAYNLNTPA SKRTKHDEIK KDLKNTKL