ID   MNHG2_STAA1             Reviewed;         145 AA.
AC   A7WZ83;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Putative antiporter subunit mnhG2;
DE   AltName: Full=Mrp complex subunit G2;
DE   AltName: Full=Putative NADH-ubiquinone oxidoreductase subunit mnhF2;
GN   Name=mnhG2; Synonyms=mrpG2; OrderedLocusNames=SAHV_0625;
OS   Staphylococcus aureus (strain Mu3 / ATCC 700698).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=418127;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu3 / ATCC 700698;
RX   PubMed=17954695; DOI=10.1128/aac.00534-07;
RA   Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K.;
RT   "Mutated response regulator graR is responsible for phenotypic conversion
RT   of Staphylococcus aureus from heterogeneous vancomycin-intermediate
RT   resistance to vancomycin-intermediate resistance.";
RL   Antimicrob. Agents Chemother. 52:45-53(2008).
CC   -!- SUBUNIT: May form a heterooligomeric complex that consists of seven
CC       subunits: mnhA2, mnhB2, mnhC2, mnhD2, mnhE2, mnhF2 and mnhG2.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G
CC       family. {ECO:0000305}.
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DR   EMBL; AP009324; BAF77508.1; -; Genomic_DNA.
DR   RefSeq; WP_000406612.1; NC_009782.1.
DR   AlphaFoldDB; A7WZ83; -.
DR   SMR; A7WZ83; -.
DR   KEGG; saw:SAHV_0625; -.
DR   HOGENOM; CLU_121334_0_3_9; -.
DR   OMA; HMLAKAA; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005451; F:monovalent cation:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0098662; P:inorganic cation transmembrane transport; IEA:InterPro.
DR   InterPro; IPR005133; PhaG_MnhG_YufB.
DR   PANTHER; PTHR34703; PTHR34703; 1.
DR   Pfam; PF03334; PhaG_MnhG_YufB; 1.
DR   TIGRFAMs; TIGR01300; CPA3_mnhG_phaG; 1.
PE   3: Inferred from homology;
KW   Antiport; Cell membrane; Ion transport; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..145
FT                   /note="Putative antiporter subunit mnhG2"
FT                   /id="PRO_0000372178"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   145 AA;  16302 MW;  BA5BE872CA6762A5 CRC64;
     MEITKEIFSL IAAVMLLLGS FIALISAIGI VKFQDVFLRS HAATKSSTLS VLLTLIGVLI
     YFIVNTGFFS VRLLLSLVFI NLTSPVGMHL VARAAYRNGA YMYRKNDAHT HASILLSSNE
     QNSTEALQLR AKKREEHRKK WYQND