ARL_ARATH
ID ARL_ARATH Reviewed; 135 AA.
AC Q8RXL7; O80578;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 105.
DE RecName: Full=ARGOS-like protein;
GN Name=ARL; OrderedLocusNames=At2g44080; ORFNames=F6E13.21;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY
RP BRASSINOSTEROIDS, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=16824178; DOI=10.1111/j.1365-313x.2006.02750.x;
RA Hu Y., Poh H.M., Chua N.-H.;
RT "The Arabidopsis ARGOS-LIKE gene regulates cell expansion during organ
RT growth.";
RL Plant J. 47:1-9(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=21457262; DOI=10.1111/j.1469-8137.2011.03710.x;
RA Feng G., Qin Z., Yan J., Zhang X., Hu Y.;
RT "Arabidopsis ORGAN SIZE RELATED1 regulates organ growth and final organ
RT size in orchestration with ARGOS and ARL.";
RL New Phytol. 191:635-646(2011).
CC -!- FUNCTION: Promotes cell expansion-dependent organ growth, probably via
CC a brassinosteroids signaling pathway. Acts downstream of BRI1.
CC {ECO:0000269|PubMed:16824178, ECO:0000269|PubMed:21457262}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC Endoplasmic reticulum {ECO:0000269|PubMed:21457262}.
CC -!- TISSUE SPECIFICITY: Expressed in cotyledons, roots, flowers, siliques
CC and leaves. {ECO:0000269|PubMed:16824178}.
CC -!- DEVELOPMENTAL STAGE: Present throughout the cotyledons as well as in
CC the mature regions of roots in young seedlings. Expressed in expanding
CC leaves, but not in leaf primordia and juvenile leaves. In flowers,
CC accumulates in sepals and stamen filaments, as well as at the apices
CC and bases of siliques. {ECO:0000269|PubMed:16824178}.
CC -!- INDUCTION: By brassinosteroids. {ECO:0000269|PubMed:16824178}.
CC -!- DOMAIN: The OSR domain is sufficient to promote organ growth.
CC {ECO:0000250}.
CC -!- DISRUPTION PHENOTYPE: Smaller lateral organs including cotyledons and
CC leaves. {ECO:0000269|PubMed:16824178}.
CC -!- SIMILARITY: Belongs to the plant organ size related (OSR) protein
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC23415.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; DQ369723; ABC96792.1; -; mRNA.
DR EMBL; AC004005; AAC23415.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002685; AEC10371.1; -; Genomic_DNA.
DR EMBL; AY080817; AAL87296.1; -; mRNA.
DR EMBL; BT000930; AAN41330.1; -; mRNA.
DR PIR; T00688; T00688.
DR RefSeq; NP_850409.1; NM_180078.4.
DR AlphaFoldDB; Q8RXL7; -.
DR BioGRID; 4350; 16.
DR IntAct; Q8RXL7; 17.
DR STRING; 3702.AT2G44080.1; -.
DR iPTMnet; Q8RXL7; -.
DR PaxDb; Q8RXL7; -.
DR PRIDE; Q8RXL7; -.
DR EnsemblPlants; AT2G44080.1; AT2G44080.1; AT2G44080.
DR GeneID; 819014; -.
DR Gramene; AT2G44080.1; AT2G44080.1; AT2G44080.
DR KEGG; ath:AT2G44080; -.
DR Araport; AT2G44080; -.
DR TAIR; locus:2051799; AT2G44080.
DR eggNOG; ENOG502S4R4; Eukaryota.
DR HOGENOM; CLU_132308_2_0_1; -.
DR InParanoid; Q8RXL7; -.
DR OMA; MTFRGSA; -.
DR OrthoDB; 1543336at2759; -.
DR PhylomeDB; Q8RXL7; -.
DR PRO; PR:Q8RXL7; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8RXL7; baseline and differential.
DR Genevisible; Q8RXL7; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0009825; P:multidimensional cell growth; IMP:TAIR.
DR GO; GO:0035265; P:organ growth; IMP:TAIR.
DR GO; GO:0046622; P:positive regulation of organ growth; IEA:InterPro.
DR GO; GO:0009741; P:response to brassinosteroid; IEP:TAIR.
DR InterPro; IPR037468; ARGOS/ARL/OSR1.
DR PANTHER; PTHR36023; PTHR36023; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Developmental protein; Endoplasmic reticulum; Membrane; Nucleus;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..135
FT /note="ARGOS-like protein"
FT /id="PRO_0000423599"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 71..122
FT /note="Organ Size Related (OSR) domain"
FT /evidence="ECO:0000250"
SQ SEQUENCE 135 AA; 15000 MW; E9A48AD42F2DD45E CRC64;
MIREFSSLQN DIINIQEHYS LNNNMDVRGD HNRKNTSFRG SAPAPIMGKQ ELFRTLSSQN
SPRRLISASY FSLESMVVLV GLTASLLILP LILPPLPPPP FMLLLIPIGI MVLLMVLAFM
PSSNSKHVSS SSTFM
