ID   ARMC1_CHICK             Reviewed;         279 AA.
AC   Q5ZMQ0;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Armadillo repeat-containing protein 1;
GN   Name=ARMC1; ORFNames=RCJMB04_1h15;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: In association with mitochondrial contact site and cristae
CC       organizing system (MICOS) complex components and mitochondrial outer
CC       membrane sorting assembly machinery (SAM) complex components may
CC       regulate mitochondrial dynamics playing a role in determining
CC       mitochondrial length, distribution and motility.
CC       {ECO:0000250|UniProtKB:Q9NVT9}.
CC   -!- SUBUNIT: Interacts with mitochondrial contact site and cristae
CC       organizing system (MICOS) complex components IMMT/MIC60 and
CC       MICOS10/MIC10 (By similarity). Interacts with mitochondrial outer
CC       membrane sorting assembly machinery (SAM) complex components SAMM50 and
CC       MTX1 (By similarity). {ECO:0000250|UniProtKB:Q9NVT9}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9NVT9}.
CC       Mitochondrion {ECO:0000250|UniProtKB:Q9NVT9}. Mitochondrion outer
CC       membrane {ECO:0000250|UniProtKB:Q9NVT9}. Note=Associates with the outer
CC       mitochondrion membrane, most likely through its C-terminus (By
CC       similarity). Not integrated into the mitochondrial outer membrane (By
CC       similarity). {ECO:0000250|UniProtKB:Q9NVT9}.
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DR   EMBL; AJ719334; CAG30993.1; -; mRNA.
DR   RefSeq; NP_001026744.1; NM_001031573.1.
DR   RefSeq; XP_015138212.1; XM_015282726.1.
DR   AlphaFoldDB; Q5ZMQ0; -.
DR   SMR; Q5ZMQ0; -.
DR   STRING; 9031.ENSGALP00000000076; -.
DR   PaxDb; Q5ZMQ0; -.
DR   Ensembl; ENSGALT00000052610; ENSGALP00000045725; ENSGALG00000036567.
DR   GeneID; 429406; -.
DR   KEGG; gga:429406; -.
DR   CTD; 55156; -.
DR   VEuPathDB; HostDB:geneid_429406; -.
DR   eggNOG; ENOG502QU5Q; Eukaryota.
DR   GeneTree; ENSGT00390000014100; -.
DR   HOGENOM; CLU_077781_0_0_1; -.
DR   InParanoid; Q5ZMQ0; -.
DR   OMA; EMNSCRR; -.
DR   OrthoDB; 1490145at2759; -.
DR   PhylomeDB; Q5ZMQ0; -.
DR   TreeFam; TF316742; -.
DR   PRO; PR:Q5ZMQ0; -.
DR   Proteomes; UP000000539; Chromosome 2.
DR   Bgee; ENSGALG00000036567; Expressed in heart and 14 other tissues.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR036163; HMA_dom_sf.
DR   InterPro; IPR016617; UCP013899_metal-bd.
DR   PANTHER; PTHR28592; PTHR28592; 1.
DR   Pfam; PF00514; Arm; 1.
DR   PIRSF; PIRSF013899; UCP013899; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF55008; SSF55008; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Membrane; Mitochondrion; Mitochondrion outer membrane;
KW   Reference proteome.
FT   CHAIN           1..279
FT                   /note="Armadillo repeat-containing protein 1"
FT                   /id="PRO_0000240885"
FT   REPEAT          36..78
FT                   /note="ARM"
FT   REGION          236..257
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..254
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   279 AA;  31063 MW;  A25323D84D8D5FA4 CRC64;
     MNSTMSDEPD ALSVVNQLRD LAADPLNRRA IVQDQGCLPG LILFLDHPSP PVVHSALLAL
     RYLAECRANR EKMKGELGMM LSLQNVIQKT TTPGETKLLA SEVYDILQSS NMSDMDNVNE
     MNYRRRKAQF FLGSTNKRAK TVVLHIDGLD DSSRRNLCEE ALLKIKGVIS FTFQMAVQRC
     VVRIRSDLKA EALATAIAST KVMKAQQVVK SESGEEMLVP FQDTPVEVEQ NTDLPEYLPE
     DESPSKEQDK AVSRVGSHPE GAASWLSTAA NFLSRSFYW