ID   ARMC1_PONAB             Reviewed;         282 AA.
AC   Q5RCR8;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Armadillo repeat-containing protein 1;
GN   Name=ARMC1;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: In association with mitochondrial contact site and cristae
CC       organizing system (MICOS) complex components and mitochondrial outer
CC       membrane sorting assembly machinery (SAM) complex components may
CC       regulate mitochondrial dynamics playing a role in determining
CC       mitochondrial length, distribution and motility.
CC       {ECO:0000250|UniProtKB:Q9NVT9}.
CC   -!- SUBUNIT: Interacts with mitochondrial contact site and cristae
CC       organizing system (MICOS) complex components IMMT/MIC60 and
CC       MICOS10/MIC10 (By similarity). Interacts with mitochondrial outer
CC       membrane sorting assembly machinery (SAM) complex components SAMM50 and
CC       MTX1 (By similarity). {ECO:0000250|UniProtKB:Q9NVT9}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9NVT9}.
CC       Mitochondrion {ECO:0000250|UniProtKB:Q9NVT9}. Mitochondrion outer
CC       membrane {ECO:0000250|UniProtKB:Q9NVT9}. Note=Associates with the outer
CC       mitochondrion membrane, most likely through its C-terminus (By
CC       similarity). Not integrated into the mitochondrial outer membrane (By
CC       similarity). {ECO:0000250|UniProtKB:Q9NVT9}.
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DR   EMBL; CR858201; CAH90439.1; -; mRNA.
DR   RefSeq; NP_001125221.1; NM_001131749.1.
DR   AlphaFoldDB; Q5RCR8; -.
DR   SMR; Q5RCR8; -.
DR   STRING; 9601.ENSPPYP00000020895; -.
DR   GeneID; 100172114; -.
DR   KEGG; pon:100172114; -.
DR   CTD; 55156; -.
DR   eggNOG; ENOG502QU5Q; Eukaryota.
DR   InParanoid; Q5RCR8; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR036163; HMA_dom_sf.
DR   InterPro; IPR016617; UCP013899_metal-bd.
DR   PANTHER; PTHR28592; PTHR28592; 1.
DR   PIRSF; PIRSF013899; UCP013899; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF55008; SSF55008; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Cytoplasm; Membrane; Mitochondrion;
KW   Mitochondrion outer membrane; Phosphoprotein; Reference proteome.
FT   CHAIN           1..282
FT                   /note="Armadillo repeat-containing protein 1"
FT                   /id="PRO_0000240884"
FT   REPEAT          39..81
FT                   /note="ARM"
FT   REGION          239..261
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        242..257
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NVT9"
FT   MOD_RES         137
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NVT9"
FT   MOD_RES         189
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NVT9"
FT   MOD_RES         246
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9D7A8"
FT   MOD_RES         260
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NVT9"
FT   MOD_RES         267
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9D7A8"
SQ   SEQUENCE   282 AA;  31221 MW;  7CDF2DCBFD7D2B12 CRC64;
     MNSSTSTMSE EPDALSVVNQ LRDLAADPLN RRAIVQDQGC LPGLILSMDH PNPPVVHSAL
     LALRYLAECR ANREKMKGEL GMMLSLQNVI QKTTTPGETK LLASEIYDIL QSSNMADGDS
     FNEMNSRRRK AQFFLGTTNK RAKTVVLHID GLDDTSRRNL CEEALLKIKG VISFTFQMAV
     QRCVVRIRSD LKAEALASAI ASTKVMKAQQ VVKSESGEEM LVPFQDTPVE VEQNTELPDY
     LPEDESPTKE QDKAVSRVGS HPEGGASWLS TAANFLSRSF YW