ID   ARMC2_BOVIN             Reviewed;         865 AA.
AC   P0C6R2;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Armadillo repeat-containing protein 2 {ECO:0000305};
GN   Name=ARMC2 {ECO:0000250|UniProtKB:Q8NEN0};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford;
RX   PubMed=19390049; DOI=10.1126/science.1169588;
RG   The bovine genome sequencing and analysis consortium;
RT   "The genome sequence of taurine cattle: a window to ruminant biology and
RT   evolution.";
RL   Science 324:522-528(2009).
CC   -!- FUNCTION: Required for sperm flagellum axoneme organization and
CC       function. Involved in axonemal central pair complex assembly and/or
CC       stability. {ECO:0000250|UniProtKB:Q3URY6}.
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DR   EMBL; AAFC03035656; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAFC03035657; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAFC03090721; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAFC03090723; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAFC03090729; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001069269.2; NM_001075801.2.
DR   AlphaFoldDB; P0C6R2; -.
DR   SMR; P0C6R2; -.
DR   STRING; 9913.ENSBTAP00000006360; -.
DR   PRIDE; P0C6R2; -.
DR   Ensembl; ENSBTAT00000006360; ENSBTAP00000006360; ENSBTAG00000036087.
DR   GeneID; 520151; -.
DR   KEGG; bta:520151; -.
DR   CTD; 84071; -.
DR   VEuPathDB; HostDB:ENSBTAG00000036087; -.
DR   VGNC; VGNC:58440; ARMC2.
DR   eggNOG; KOG1048; Eukaryota.
DR   GeneTree; ENSGT00390000000663; -.
DR   InParanoid; P0C6R2; -.
DR   OMA; NDVAMEY; -.
DR   OrthoDB; 741009at2759; -.
DR   Proteomes; UP000009136; Chromosome 9.
DR   Bgee; ENSBTAG00000036087; Expressed in oocyte and 109 other tissues.
DR   ExpressionAtlas; P0C6R2; baseline.
DR   GO; GO:0044782; P:cilium organization; IBA:GO_Central.
DR   GO; GO:0007288; P:sperm axoneme assembly; ISS:UniProtKB.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR038905; ARMC2.
DR   PANTHER; PTHR21356; PTHR21356; 1.
DR   SMART; SM00185; ARM; 5.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Differentiation; Reference proteome; Repeat; Spermatogenesis.
FT   CHAIN           1..865
FT                   /note="Armadillo repeat-containing protein 2"
FT                   /id="PRO_0000325089"
FT   REPEAT          261..300
FT                   /note="ARM 1"
FT   REPEAT          303..343
FT                   /note="ARM 2"
FT   REPEAT          362..402
FT                   /note="ARM 3"
FT   REPEAT          407..448
FT                   /note="ARM 4"
FT   REPEAT          461..502
FT                   /note="ARM 5"
FT   REPEAT          505..546
FT                   /note="ARM 6"
FT   REPEAT          550..587
FT                   /note="ARM 7"
FT   REPEAT          589..614
FT                   /note="ARM 8"
FT   REPEAT          617..660
FT                   /note="ARM 9"
FT   REPEAT          662..703
FT                   /note="ARM 10"
FT   REPEAT          705..744
FT                   /note="ARM 11"
FT   REPEAT          746..788
FT                   /note="ARM 12"
FT   REGION          39..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          214..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   865 AA;  96936 MW;  6FB0DE9479074931 CRC64;
     MLSPNDKKLE KLDPFYLPSL SKQKTSAEIV SEARNALRTV RTQRPFTPRE DQRKLFGPAS
     SRTPENRPPS SFSVHASSFE FSDSRPISGT RLSPLEFKPK APASPDTVED FCLSFPKPPV
     DPAKIRRISS ARARLFRVAS QGALLPARTL LPTQPTRVES EETVTTRDSV VKINGIYLTE
     SKAIGHLKRH PLQLTYDGDF SKITEQEMFK GATSVPFHLR SGGDQGKRRP RASSSSRSPD
     QSRLDIRAGS KADLQEKNTE IEVDEVFWNT RIVPILHDLE KEENIEMVCA TCTQLHHALE
     EGNMLGNKFK RRSVLLKTLY KLVDVGSDLL SLKLAKIILA LKVSGKNLLN VCKLIFKISR
     SEKNDSLIRN DSILESLLEV LRSEDLQANT EAFLYCMGTI KFISGNPEFL HEMMGKGAVE
     ILMSLIKQVN ENTKKSGTCL PNSGHLLVQM TATLRNLVDS PLARSKLLSI NALPQLCTVM
     EQHIGDKDVC TNIARIFSKL TSYHDCCVAL ASYSRCYALF LNLINKYQKK QDLVVRVVFI
     LGNLTAKNNQ AREQFSKEKG SIPTLLSLFH TFYKLDLHSG KRWGEGDERP EARRPAQAED
     VLIKLTRVLA NLAIHPGVGP AIAAHSHIVG LLLATLESKS IDDCEELVIN TTATINNLSY
     YKVKNSIIQD RKLYIAELLL KLLVSNNMDG ILEAVRVFGN LSQDHDICDF IVQKNVHKFM
     IALLDAKHQD ICFSACGVLL NLTVDRDKRL ILKEGGGIKK LVDCLRDFGP TDWQLASLVC
     KTLWNFSENI TNAASCFGDE AANTLLALLS SFLDEELALN GSFDQDLKNY HKLHWETEFR
     PVAQQLLNRI KNHHTFLEPL PIPSF