ID   ARMD1_HUMAN             Reviewed;         440 AA.
AC   Q6PIY5; A1KXE5;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 2.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Armadillo-like helical domain containing protein 1 {ECO:0000305};
DE   AltName: Full=p40;
GN   Name=ARMH1 {ECO:0000312|HGNC:HGNC:34345}; Synonyms=C1orf228, NCRNA00082;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 71-440 (ISOFORM 1).
RA   Heese K.;
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q6PIY5-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q6PIY5-2; Sequence=VSP_031683;
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DR   EMBL; CH471059; EAX07027.1; -; Genomic_DNA.
DR   EMBL; BC026115; AAH26115.1; -; mRNA.
DR   EMBL; AY254217; AAP80384.1; -; mRNA.
DR   CCDS; CCDS53311.1; -. [Q6PIY5-1]
DR   RefSeq; NP_001139108.1; NM_001145636.1. [Q6PIY5-1]
DR   AlphaFoldDB; Q6PIY5; -.
DR   BioGRID; 130905; 6.
DR   IntAct; Q6PIY5; 1.
DR   STRING; 9606.ENSP00000420716; -.
DR   iPTMnet; Q6PIY5; -.
DR   PhosphoSitePlus; Q6PIY5; -.
DR   BioMuta; C1orf228; -.
DR   DMDM; 190359055; -.
DR   EPD; Q6PIY5; -.
DR   MassIVE; Q6PIY5; -.
DR   PaxDb; Q6PIY5; -.
DR   PeptideAtlas; Q6PIY5; -.
DR   PRIDE; Q6PIY5; -.
DR   Antibodypedia; 50330; 27 antibodies from 11 providers.
DR   DNASU; 339541; -.
DR   Ensembl; ENST00000458657.6; ENSP00000420716.1; ENSG00000198520.12. [Q6PIY5-1]
DR   Ensembl; ENST00000535358.6; ENSP00000440524.1; ENSG00000198520.12. [Q6PIY5-1]
DR   GeneID; 339541; -.
DR   KEGG; hsa:339541; -.
DR   MANE-Select; ENST00000535358.6; ENSP00000440524.1; NM_001145636.2; NP_001139108.1.
DR   UCSC; uc001cmf.2; human. [Q6PIY5-1]
DR   CTD; 339541; -.
DR   DisGeNET; 339541; -.
DR   GeneCards; ARMH1; -.
DR   HGNC; HGNC:34345; ARMH1.
DR   HPA; ENSG00000198520; Tissue enhanced (fallopian tube, testis).
DR   neXtProt; NX_Q6PIY5; -.
DR   OpenTargets; ENSG00000198520; -.
DR   PharmGKB; PA164717053; -.
DR   VEuPathDB; HostDB:ENSG00000198520; -.
DR   eggNOG; ENOG502QQAX; Eukaryota.
DR   GeneTree; ENSGT00390000001593; -.
DR   HOGENOM; CLU_057628_1_0_1; -.
DR   InParanoid; Q6PIY5; -.
DR   OMA; QFFVQTF; -.
DR   OrthoDB; 526619at2759; -.
DR   PhylomeDB; Q6PIY5; -.
DR   TreeFam; TF329061; -.
DR   PathwayCommons; Q6PIY5; -.
DR   SignaLink; Q6PIY5; -.
DR   BioGRID-ORCS; 339541; 20 hits in 1061 CRISPR screens.
DR   GenomeRNAi; 339541; -.
DR   Pharos; Q6PIY5; Tdark.
DR   PRO; PR:Q6PIY5; -.
DR   Proteomes; UP000005640; Chromosome 1.
DR   RNAct; Q6PIY5; protein.
DR   Bgee; ENSG00000198520; Expressed in right uterine tube and 99 other tissues.
DR   ExpressionAtlas; Q6PIY5; baseline and differential.
DR   Genevisible; Q6PIY5; HS.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR041090; DUF5578.
DR   PANTHER; PTHR34258; PTHR34258; 1.
DR   Pfam; PF17741; DUF5578; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..440
FT                   /note="Armadillo-like helical domain containing protein 1"
FT                   /id="PRO_0000320611"
FT   VAR_SEQ         308..440
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:15489334"
FT                   /id="VSP_031683"
SQ   SEQUENCE   440 AA;  48855 MW;  52B3C78A4AE52CCB CRC64;
     MTSIKEQAAI SRLLSFLQEW DNAGKVARSH ILDKFIETNQ GKTAPELEQE FSQGASLFLV
     RLTTSLRITY MTDSCLEKLL RSIGIFLSAV SSNRYLIEFL EVGGVLTLLE ILGLEKIKEE
     AKKESVKLLQ VIANSGRTYK ELICESYGVR SIAEFLAKSK SEETQEEVQV LLDSLVHGNP
     KYQNQVYKGL IALLPCESPK AQQLSLQTLR TAQPIIGTTH PSIVDCVLKV LGTMHLEVQY
     EAIELIKDLV GYDVRQALLK GLVALLIPSV KEISKLQAKI LSDPSVLQLT PSLPMFLQQA
     AAAKAIGVLA RNDMSIAEEL LYLRVVRGLM AAMGNTDHSN SQRLASLTLE CFVQMFPLVA
     EHVRKCMGEE LYQLFLSNAE DLYMKIDSIQ ADILAANTVN VTKALCLHGS SYSMNTLYGS
     RDSAQMAYLT HFEEDVESKE