ARMD3_DANRE
ID ARMD3_DANRE Reviewed; 689 AA.
AC Q6PGW3;
DT 17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 04-NOV-2008, sequence version 2.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Armadillo-like helical domain-containing protein 3 {ECO:0000250|UniProtKB:Q5T2E6};
GN Name=armh3 {ECO:0000250|UniProtKB:Q5T2E6}; ORFNames=zgc:63733;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=AB;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in Golgi maintenance and protein secretion.
CC {ECO:0000250|UniProtKB:Q5T2E6}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000250|UniProtKB:Q5T2E6}; Single-pass membrane protein
CC {ECO:0000255}. Cytoplasm {ECO:0000250|UniProtKB:Q5T2E6}.
CC -!- SIMILARITY: Belongs to the ARMH3 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH56810.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; BC056810; AAH56810.1; ALT_INIT; mRNA.
DR RefSeq; NP_956913.2; NM_200619.2.
DR AlphaFoldDB; Q6PGW3; -.
DR STRING; 7955.ENSDARP00000103797; -.
DR PaxDb; Q6PGW3; -.
DR Ensembl; ENSDART00000162211; ENSDARP00000140852; ENSDARG00000104285.
DR GeneID; 393591; -.
DR KEGG; dre:393591; -.
DR CTD; 79591; -.
DR ZFIN; ZDB-GENE-040426-1249; armh3.
DR eggNOG; KOG4654; Eukaryota.
DR GeneTree; ENSGT00390000002554; -.
DR HOGENOM; CLU_029861_2_0_1; -.
DR InParanoid; Q6PGW3; -.
DR OMA; GFWTEFF; -.
DR OrthoDB; 1024171at2759; -.
DR PhylomeDB; Q6PGW3; -.
DR TreeFam; TF300220; -.
DR PRO; PR:Q6PGW3; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 22.
DR Bgee; ENSDARG00000104285; Expressed in blastula and 21 other tissues.
DR GO; GO:0005829; C:cytosol; ISS:UniProtKB.
DR GO; GO:0000139; C:Golgi membrane; ISS:UniProtKB.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:1903358; P:regulation of Golgi organization; ISS:UniProtKB.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR039868; ARMD3-like.
DR InterPro; IPR013636; ARMH3_C.
DR PANTHER; PTHR13608; PTHR13608; 1.
DR Pfam; PF08427; DUF1741; 1.
DR SMART; SM01158; DUF1741; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..689
FT /note="Armadillo-like helical domain-containing protein 3"
FT /id="PRO_0000284517"
FT TRANSMEM 520..538
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 689 AA; 78779 MW; 3B84EE1E3984C568 CRC64;
MAQTEKKAGL LRRTSSSKKP LKEKVVLMYD EIFMKEDPTK NSPRFWDELF LMKVNLEYLE
GKLESLDGDE FMKIKDNINS LFHHCVQALA EEHQIKVVNA LQTLCALFRG VHQKNKSATG
FDIINMLIGF DKAELRMKEL MESLDSLLCG DGSESLKSLC LKLLLCLVTV TDNISQNTIL
EYVMINSIFE AILQILSDVS SRSQHGYDSV VLLALLVNYR KYESVNPYIV KLSIVDDEPT
LDGLGMVIHH ALTEYNRQYK EKEEENQGGF FSTLSSMVGS MFIADADEKL SVQTNEAILL
ALYEAVHLNR NFITVLAQSH PEIDMAATPA TPVPASPTTP LGTTPPSLDL MNNPELPLDP
NLQTSNLLIT FLKYSSIVMQ DTKDEHRLNS ARLCLIILTC IAEDQYADAF LHDDNMNFRV
NLHRMPMRHR KKAADKNIPC RPLVCAVLDL MVEFVVTHMM KEFPMDLYVR CVQIIHKLIC
YQKKCRVRLH YTWRELWSAL INLLKFLLSN ETGLLAKHNI FQLALQVVNL FNMFITYGDT
FLPTPSSYDE LYYEIIRMHQ VFDNLYCMVL RVSTNAGQWK EPASKVTHAL VNVRAIINHF
NPKIESYAAV NHISQLSEDQ VLEVVRSNYD TLTLKLQDGL DQFERYSEQP REAGFFKELV
RSISLNVRKN VSLTTMSQDV LLKEFSSIS