ID   ARMD4_BOVIN             Reviewed;         760 AA.
AC   Q2TA21;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Armadillo-like helical domain-containing protein 4 {ECO:0000250|UniProtKB:Q86TY3};
DE   Flags: Precursor;
GN   Name=ARMH4 {ECO:0000250|UniProtKB:Q86TY3};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
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DR   EMBL; BC111157; AAI11158.1; -; mRNA.
DR   RefSeq; NP_001033149.1; NM_001038060.1.
DR   AlphaFoldDB; Q2TA21; -.
DR   STRING; 9913.ENSBTAP00000027817; -.
DR   PaxDb; Q2TA21; -.
DR   PRIDE; Q2TA21; -.
DR   GeneID; 508562; -.
DR   KEGG; bta:508562; -.
DR   CTD; 145407; -.
DR   eggNOG; ENOG502QWJQ; Eukaryota.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR031524; ARMH4.
DR   PANTHER; PTHR21585; PTHR21585; 1.
DR   Pfam; PF15767; DUF4696; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..760
FT                   /note="Armadillo-like helical domain-containing protein 4"
FT                   /id="PRO_0000252151"
FT   TOPO_DOM        28..700
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        701..721
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        722..760
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          49..69
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          117..143
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          216..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          373..392
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          474..495
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          536..652
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..143
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        227..243
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        378..392
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        574..591
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        594..633
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         755
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86TY3"
FT   MOD_RES         756
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86TY3"
FT   CARBOHYD        56
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   760 AA;  82393 MW;  E9793DD2A4E66473 CRC64;
     MSRPIVLHIC LAFCSLLLLN FAAQCLAFPN LERREIVLLH AEKGQSERLN TDDLENDSVT
     SNTPVSGDPM IVLAGPSTMS LNKVFPSNKE TSPVGAGLMQ ADGSNIYTAT EPEVPAGEEV
     FGSSQPERMS PESRPSKATL TNPVMPTASL NIDEREEPSR GTIIQPTVEG TTEATQGFLS
     YVDDQLFATE SPEGLSLGHS PLSLVNTKEM LTTSPRTEKF EANPEHKTTS FPGSKLTAGT
     EPSQMTADNT QATAATKHWL PTSESILSVE PETDSLLGAP EVTTSVSTAV AAAPVISDEW
     DDTKLESVSQ IKTPKLGDNT ETQVRMEISQ TTQAPDIGME VMEEGKALTE AADVSLKLPE
     METHMETTLP MAHGGERASD QSSVTPTSPM GDTKVSVMNL VQDTADFVES TKENGAMFLE
     TTVSISEYES EVHQPLGNRF KDIITQEMTT AVQAAEATVS LVTQEQQVAT LEVTRGEDET
     KGGRELPSAT VDAPRATQLS RRWEPLATVV STTPIPVSFK VTPAVEDVMD TVTGPNEELF
     TPILGSPVTP PGITEEAPST SPALADPEAS SERRTAAPSF SYVNTAASYG LDQLESEEGE
     DDEDEEDEEE EDEEEEDEEE DEEDKDADSL DEALGDTELP GFTLPGITSQ EPGLEQENVV
     SLEGVTFQVP DAIQWEQQNQ GLVRSWMEKL KDKAGYMSGM LVPVGVGIAG ALFILGALYS
     IKVMNRRRRN GFKRHKRKQR EFNSMQDRVM LLADSSEDEF