ID   ARMX6_RAT               Reviewed;         301 AA.
AC   Q66HF0;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Protein ARMCX6;
GN   Name=Armcx6;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May regulate the dynamics and distribution of mitochondria in
CC       neural cells. {ECO:0000250|UniProtKB:Q8K3A6}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q8K3A6}.
CC       Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8BHS6}; Single-
CC       pass membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the eutherian X-chromosome-specific Armcx
CC       family. {ECO:0000305}.
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DR   EMBL; BC081893; AAH81893.1; -; mRNA.
DR   RefSeq; NP_001007758.1; NM_001007757.1.
DR   RefSeq; XP_008771647.1; XM_008773425.2.
DR   RefSeq; XP_017457600.1; XM_017602111.1.
DR   RefSeq; XP_017457601.1; XM_017602112.1.
DR   RefSeq; XP_017457602.1; XM_017602113.1.
DR   AlphaFoldDB; Q66HF0; -.
DR   STRING; 10116.ENSRNOP00000035673; -.
DR   PhosphoSitePlus; Q66HF0; -.
DR   PaxDb; Q66HF0; -.
DR   PRIDE; Q66HF0; -.
DR   Ensembl; ENSRNOT00000029807; ENSRNOP00000035673; ENSRNOG00000037707.
DR   GeneID; 363496; -.
DR   KEGG; rno:363496; -.
DR   UCSC; RGD:1359303; rat.
DR   CTD; 54470; -.
DR   RGD; 1359303; Armcx6.
DR   eggNOG; ENOG502RP3G; Eukaryota.
DR   GeneTree; ENSGT00940000163042; -.
DR   HOGENOM; CLU_037187_0_1_1; -.
DR   InParanoid; Q66HF0; -.
DR   OMA; FIQGKMW; -.
DR   OrthoDB; 949439at2759; -.
DR   PhylomeDB; Q66HF0; -.
DR   TreeFam; TF335652; -.
DR   PRO; PR:Q66HF0; -.
DR   Proteomes; UP000002494; Chromosome X.
DR   Bgee; ENSRNOG00000037707; Expressed in pancreas and 19 other tissues.
DR   Genevisible; Q66HF0; RN.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   InterPro; IPR006911; ARM-rpt_dom.
DR   Pfam; PF04826; Arm_2; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion outer membrane; Reference proteome;
KW   Signal-anchor; Transmembrane; Transmembrane helix.
FT   CHAIN           1..301
FT                   /note="Protein ARMCX6"
FT                   /id="PRO_0000191376"
FT   TOPO_DOM        1..7
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000250|UniProtKB:Q8BHS6"
FT   TRANSMEM        8..25
FT                   /note="Helical; Signal-anchor"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        26..301
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q8BHS6"
FT   REGION          1..6
FT                   /note="Mitochondrion outer membrane (MOM)-targeting
FT                   sequence"
FT                   /evidence="ECO:0000305"
FT   REGION          26..36
FT                   /note="Mitochondrion outer membrane (MOM)-targeting
FT                   sequence"
FT                   /evidence="ECO:0000305"
FT   REGION          70..105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   301 AA;  33374 MW;  8C71EA397C990643 CRC64;
     MGRAREMGWM AAGLMIGAGA CYCMYKLTMG RDEGNELENE EEDEWDDEQD LDEEEADIWF
     DFTAMARPWS EDGEWDEPGA PGGTEDRRSG GGKANRAHPT KQRPFPYEHK NIWGVQSFQT
     FPCALNLTKC AFSQGKKMFT ESTIAGFSLT HNVSRHLSSL SVVGSRSPTP QPTVREKALD
     VPEHPNSSIE NQDQIKMYID EVCRDAVFCC CKSFLQQAGL GLLISMTVIN NMLAKSLSDP
     KFPLLSEGSG CAKVQGLEAQ MSLPEKPVLA EEVLAAQMLF SFMCLFTRSG SREMLVEAIS
     P