ID   MNN9_CANAL              Reviewed;         368 AA.
AC   P53697; A0A1D8PKF7; Q5A4F1;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 118.
DE   RecName: Full=Mannan polymerase complex subunit MNN9;
GN   Name=MNN9; OrderedLocusNames=CAALFM_C306020WA; ORFNames=CaO19.7383;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 10261 / CBS 2718 / NBRC 1061;
RX   PubMed=10601199; DOI=10.1128/jb.181.24.7439-7448.1999;
RA   Southard S.B., Specht C.A., Mishra C., Chen-Weiner J., Robbins P.W.;
RT   "Molecular analysis of the Candida albicans homolog of Saccharomyces
RT   cerevisiae MNN9, required for glycosylation of cell wall mannoproteins.";
RL   J. Bacteriol. 181:7439-7448(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Required for the addition of the long alpha 1,6-mannose
CC       backbone of N-linked glycans on cell wall and periplasmic proteins.
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000250|UniProtKB:P39107}; Single-pass type II membrane protein
CC       {ECO:0000250|UniProtKB:P39107}.
CC   -!- SIMILARITY: Belongs to the ANP1/MMN9/VAN1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U63642; AAB05924.1; -; Genomic_DNA.
DR   EMBL; CP017625; AOW28610.1; -; Genomic_DNA.
DR   RefSeq; XP_716624.1; XM_711531.1.
DR   AlphaFoldDB; P53697; -.
DR   SMR; P53697; -.
DR   BioGRID; 1224829; 1.
DR   STRING; 237561.P53697; -.
DR   CAZy; GT62; Glycosyltransferase Family 62.
DR   GeneID; 3641735; -.
DR   KEGG; cal:CAALFM_C306020WA; -.
DR   CGD; CAL0000179486; MNN9.
DR   VEuPathDB; FungiDB:C3_06020W_A; -.
DR   eggNOG; ENOG502QRPX; Eukaryota.
DR   HOGENOM; CLU_017872_4_0_1; -.
DR   InParanoid; P53697; -.
DR   OMA; LVYHYNE; -.
DR   OrthoDB; 1331726at2759; -.
DR   UniPathway; UPA00378; -.
DR   Proteomes; UP000000559; Chromosome 3.
DR   GO; GO:0005801; C:cis-Golgi network; IEA:EnsemblFungi.
DR   GO; GO:0000136; C:mannan polymerase complex; IBA:GO_Central.
DR   GO; GO:0000009; F:alpha-1,6-mannosyltransferase activity; IEA:EnsemblFungi.
DR   GO; GO:0000030; F:mannosyltransferase activity; IMP:CGD.
DR   GO; GO:0000032; P:cell wall mannoprotein biosynthetic process; IMP:CGD.
DR   GO; GO:0034605; P:cellular response to heat; IMP:CGD.
DR   GO; GO:0030447; P:filamentous growth; IMP:CGD.
DR   GO; GO:0036180; P:filamentous growth of a population of unicellular organisms in response to biotic stimulus; IMP:CGD.
DR   GO; GO:0036168; P:filamentous growth of a population of unicellular organisms in response to heat; IMP:CGD.
DR   GO; GO:0031505; P:fungal-type cell wall organization; IMP:CGD.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IBA:GO_Central.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Reference proteome; Signal-anchor;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..368
FT                   /note="Mannan polymerase complex subunit MNN9"
FT                   /id="PRO_0000193669"
FT   TOPO_DOM        1..15
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        16..33
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT   TOPO_DOM        34..368
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   368 AA;  42782 MW;  930DCC64EE8F5EF5 CRC64;
     MVHYRNRYLN YIRRKPLALL APITLLVVIY FYFFSAHGFS SNKQKYNYNK KSRGWFYKNR
     DTVILKDLPK NHISHYDLNK LTASKDALNK REEVLILTPM SKFLPEYWEN INKLTYDHSL
     ISLGFIFPRT TQGDDALKEL ENALKKTKRE KRLNFKKITI LRQDSNSLQS QLEKDRHAFK
     VQKERRSMMA LARNSLVFST ILPSTSWVLW LDADIVETPV TLIQDLTGHN KPVVSANVHQ
     RFINQDTKQP DIRPYDFNNW VESEEGLKLA ASLPDDEIIV EGYSEMVTHR ALMAHFYDPK
     GDPSTEMTLD GVGGGAVMVK ADVHRDGAMF PSFPFYHLIE TEGFAKMAKR LGYEVYGLPN
     YLVFHYNE