ID   MNTH_BLOPB              Reviewed;         411 AA.
AC   Q492G8;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Divalent metal cation transporter MntH {ECO:0000255|HAMAP-Rule:MF_00221};
GN   Name=mntH {ECO:0000255|HAMAP-Rule:MF_00221}; OrderedLocusNames=BPEN_518;
OS   Blochmannia pennsylvanicus (strain BPEN).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; ant endosymbionts; Candidatus Blochmannia.
OX   NCBI_TaxID=291272;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BPEN;
RX   PubMed=16077009; DOI=10.1101/gr.3771305;
RA   Degnan P.H., Lazarus A.B., Wernegreen J.J.;
RT   "Genome sequence of Blochmannia pennsylvanicus indicates parallel
RT   evolutionary trends among bacterial mutualists of insects.";
RL   Genome Res. 15:1023-1033(2005).
CC   -!- FUNCTION: H(+)-stimulated, divalent metal cation uptake system.
CC       {ECO:0000255|HAMAP-Rule:MF_00221}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00221}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00221}.
CC   -!- SIMILARITY: Belongs to the NRAMP family. {ECO:0000255|HAMAP-
CC       Rule:MF_00221}.
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DR   EMBL; CP000016; AAZ41131.1; -; Genomic_DNA.
DR   RefSeq; WP_011283042.1; NC_007292.1.
DR   AlphaFoldDB; Q492G8; -.
DR   SMR; Q492G8; -.
DR   STRING; 291272.BPEN_518; -.
DR   EnsemblBacteria; AAZ41131; AAZ41131; BPEN_518.
DR   KEGG; bpn:BPEN_518; -.
DR   eggNOG; COG1914; Bacteria.
DR   HOGENOM; CLU_020088_2_0_6; -.
DR   OMA; IATFVNS; -.
DR   BioCyc; CBLO291272:BPEN_RS02560-MON; -.
DR   Proteomes; UP000007794; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00221; NRAMP; 1.
DR   InterPro; IPR001046; NRAMP_fam.
DR   PANTHER; PTHR11706; PTHR11706; 1.
DR   Pfam; PF01566; Nramp; 1.
DR   PRINTS; PR00447; NATRESASSCMP.
DR   TIGRFAMs; TIGR01197; nramp; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..411
FT                   /note="Divalent metal cation transporter MntH"
FT                   /id="PRO_1000024099"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        289..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        323..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        349..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        390..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
SQ   SEQUENCE   411 AA;  44882 MW;  25FC4C3689728702 CRC64;
     MLNEQDSVTE HRSRRKIKFA LLGPAFIAAI GYIDPGNFAT NIQAGATFGY QLLWVVVWAN
     IMAMLIQLLS AKLGIATGKN LAEHIRDQFP RSVVWMYWIQ AEIIAMATDL AEFIGAAIGF
     KILLGIPLLQ GALLTGLITF LILTLQRYGK KPLEFVVGGL LFFVAIAYVI ELFYSKPKFI
     MLGMSMLLPI LPNREAVFLS AGVLGATIMP HVIYLHSSLT QDESKTASRS ERYSSTKLDV
     AIAMTIAGFV NLSMMATAAA VFHYGGYTGI SNLDEAYLTL SPLLNHTAAI VFGLSLTAAG
     LSSTVVGTLA GQVVMQGFVR FHIPLLLRRV ITMLPSFIVI SFGIDSTRIL IMSQVLLSFG
     IALALIPLLV FTGNVKLMNE LVNSLWIKLI GWLITIVVII LNIYLLIGII I