ID   MNTH_BURCM              Reviewed;         441 AA.
AC   Q0B8F7;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Divalent metal cation transporter MntH {ECO:0000255|HAMAP-Rule:MF_00221};
GN   Name=mntH {ECO:0000255|HAMAP-Rule:MF_00221}; OrderedLocusNames=Bamb_4013;
OS   Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia
OS   (strain AMMD)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=339670;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-244 / AMMD;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P.,
RA   Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K.,
RA   Ramette A., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 2 of Burkholderia cepacia AMMD.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: H(+)-stimulated, divalent metal cation uptake system.
CC       {ECO:0000255|HAMAP-Rule:MF_00221}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00221}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00221}.
CC   -!- SIMILARITY: Belongs to the NRAMP family. {ECO:0000255|HAMAP-
CC       Rule:MF_00221}.
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DR   EMBL; CP000441; ABI89566.1; -; Genomic_DNA.
DR   RefSeq; WP_011659012.1; NZ_CP009799.1.
DR   AlphaFoldDB; Q0B8F7; -.
DR   SMR; Q0B8F7; -.
DR   STRING; 339670.Bamb_4013; -.
DR   EnsemblBacteria; ABI89566; ABI89566; Bamb_4013.
DR   GeneID; 44694632; -.
DR   KEGG; bam:Bamb_4013; -.
DR   PATRIC; fig|339670.21.peg.4293; -.
DR   eggNOG; COG1914; Bacteria.
DR   OMA; SPKWLRY; -.
DR   Proteomes; UP000000662; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00221; NRAMP; 1.
DR   InterPro; IPR001046; NRAMP_fam.
DR   PANTHER; PTHR11706; PTHR11706; 1.
DR   Pfam; PF01566; Nramp; 1.
DR   PRINTS; PR00447; NATRESASSCMP.
DR   TIGRFAMs; TIGR01197; nramp; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..441
FT                   /note="Divalent metal cation transporter MntH"
FT                   /id="PRO_0000325601"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        223..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        360..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        381..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        419..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
SQ   SEQUENCE   441 AA;  46420 MW;  EF769E1561071A3E CRC64;
     MIPVTSKSSS GFALPDLSTD RAHRAVPAEG AARAALEGRR TGIAALLPFV GPAVIASIGY
     MDPGNFATNI QAGAAYGYRL LWVVLAANAI AMLFQAMSAK LGIVTGRNLA ELCREHFPAP
     IVWGMWIASE IAAMATDLAE FLGGALAFAL LCHLPLFAGM IATALATCAI LALEKRGFRP
     LEAAIAALVG VIGACYLGEL MIAPQDWHAA AFHLVVPQIP DRAALTIAVG IIGATIMPHT
     LYLHSGLTQD RIAPRDDTER RRLMRFSNRE VVVALGLAGF VNLAMVMMAA SAFHASAPGM
     ADIGDAYHTL IPVLGPAAGV LFLVALLTSG VSSSVVGTMA GQVVMQGFMR RRLSVWMRRA
     VTIAPAFAVV ACGCDVTRAM VASQVVLSFV LPMPMIALLI LSARNDVMGR YAMRMPLRIV
     AGTATVVIVG LNAYLVWAAF N