ID   MNTH_YERP3              Reviewed;         409 AA.
AC   A7FGC8;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Divalent metal cation transporter MntH {ECO:0000255|HAMAP-Rule:MF_00221};
GN   Name=mntH {ECO:0000255|HAMAP-Rule:MF_00221};
GN   OrderedLocusNames=YpsIP31758_1327;
OS   Yersinia pseudotuberculosis serotype O:1b (strain IP 31758).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=349747;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP 31758;
RX   PubMed=17784789; DOI=10.1371/journal.pgen.0030142;
RA   Eppinger M., Rosovitz M.J., Fricke W.F., Rasko D.A., Kokorina G.,
RA   Fayolle C., Lindler L.E., Carniel E., Ravel J.;
RT   "The complete genome sequence of Yersinia pseudotuberculosis IP31758, the
RT   causative agent of Far East scarlet-like fever.";
RL   PLoS Genet. 3:1508-1523(2007).
CC   -!- FUNCTION: H(+)-stimulated, divalent metal cation uptake system.
CC       {ECO:0000255|HAMAP-Rule:MF_00221}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00221}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00221}.
CC   -!- SIMILARITY: Belongs to the NRAMP family. {ECO:0000255|HAMAP-
CC       Rule:MF_00221}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000720; ABS48538.1; -; Genomic_DNA.
DR   RefSeq; WP_002211621.1; NC_009708.1.
DR   AlphaFoldDB; A7FGC8; -.
DR   SMR; A7FGC8; -.
DR   EnsemblBacteria; ABS48538; ABS48538; YpsIP31758_1327.
DR   GeneID; 66844874; -.
DR   KEGG; ypi:YpsIP31758_1327; -.
DR   HOGENOM; CLU_020088_2_0_6; -.
DR   OMA; IATFVNS; -.
DR   Proteomes; UP000002412; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00221; NRAMP; 1.
DR   InterPro; IPR001046; NRAMP_fam.
DR   PANTHER; PTHR11706; PTHR11706; 1.
DR   Pfam; PF01566; Nramp; 1.
DR   PRINTS; PR00447; NATRESASSCMP.
DR   TIGRFAMs; TIGR01197; nramp; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..409
FT                   /note="Divalent metal cation transporter MntH"
FT                   /id="PRO_1000058657"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        155..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        290..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        320..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        348..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
FT   TRANSMEM        388..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00221"
SQ   SEQUENCE   409 AA;  43742 MW;  1E9963848CAF877D CRC64;
     MLNGRAVDTS RRPLRKIKLS LMGPAFIAAI AYIDPGNFAT NIQAGATFGY TLLWVVVWAN
     VMAMLVQLLS AKLGIATGKN LAEHIRDRFP RPVVWAYWVQ AEIIVMATDL AEFIGAAIGF
     KLLFGVTLLQ GAVLTGIATF LILMLQNRGQ KPLELVIGGL LLFVAAAYIV ELIFSQPDIA
     ALGRGMLIPN LPDGNAVFLA AGVLGATIMP HVIYLHSALT QTGGEESKTE RYASTKFDVA
     IAMTIAGFVN LAMMATAAAA FHFNGYENIA EIEEAYITLQ PLLGNAAATV FGLSLIAAGL
     SSTVVGTLAG QVVMQGFVRF YIPMWVRRIV TMLPSFIVIL AGMDATQILV MSQVLLSFGI
     ALALVPLLVF TGNKELMGEL VDTKTTQILG KLVVLIVVGL NAYLLISLL